Gold modified polydopamine coated mesoporous silica nano-structures for synergetic chemo-photothermal effect

Rahoui, Nahla; Jiang, Bo; Hegazy, Mohammad; Taloub, Nadia; Wang, Yuanlin; Yu, Miao; Huang, Yu Dong

doi:10.1016/j.colsurfb.2018.07.015

Cited by 52 publications

(19 citation statements)

References 40 publications

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“…Once the hyperthermia capability of the formulations after a single shot of NIR light was demonstrated, the next step was to elucidate whether the formulations could be useful as depots of gold nanoparticles that provide localized elevations of temperature each time the zone is irradiated. The reproducibility of the photothermal effects has been barely reported in literature [37] and for some materials, irreversible changes and inactivation after the first shot of radiation have been observed [38]. Therefore, for a biomedical application, the reproducibility of the NIR-induced heating should be verified.…”

Section: Resultsmentioning

confidence: 99%

Syringeable Self-Organizing Gels that Trigger Gold Nanoparticle Formation for Localized Thermal Ablation

et al. 2019

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Block copolymer dispersions that form gels at body temperature and that additionally are able to reduce a gold salt to nanoparticles (AuNPs) directly in the final formulation under mild conditions were designed as hybrid depots for photothermal therapy. The in situ gelling systems may retain AuNPs in the application zone for a long time so that localized elevations of temperature can be achieved each time the zone is irradiated. To carry out the work, dispersions were prepared covering a wide range of poloxamine Tetronic 1307:gold salt molar ratios in NaCl media (also varying from pure water to hypertonic solution). Even at copolymer concentrations well above the critical micelle concentration, the reducing power of the copolymer was maintained, and AuNPs were formed in few hours without extra additives. Varying the copolymer and NaCl concentrations allowed a fine tuning of nanoparticles’ shape from spherical to triangular nanoplates, which determined that the surface plasmon resonance showed a maximum intensity at 540 nm or at 1000 nm, respectively. The information gathered on the effects of (i) the poloxamine concentration on AuNPs’ size and shape under isotonic conditions, (ii) the AuNPs on the temperature-induced gelling transition, and (iii) the gel properties on the photothermal responsiveness of the AuNPs during successive irradiation cycles may help the rational design of one-pot gels with built-in temperature and light responsiveness.

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Section: Resultsmentioning

confidence: 99%

Syringeable Self-Organizing Gels that Trigger Gold Nanoparticle Formation for Localized Thermal Ablation

et al. 2019

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“…The peak at 1648 cm −1 can be assigned stretching vibration of aromatic ring and overlapped bending vibration of N H. The peaks at 1510 and 1125 cm −1 can be ascribed to N H shearing vibration of the amide group and the C O stretching vibration, respectively (Jiang et al, 2018;Cao et al, 2018). Thus, the presence of the N H vibration of amide groups can show the coating of biosilica with PDA polymer via surface polymerization (Rahouia et al, 2018;Cao et al, 2018). The FTIR spectra of the biosilica-TEPA-PDA display some new peaks compared to those of the acid treated and PDA grafted biosilica (Fig.…”

Section: Characterization Of Diatomic Bio-silica Particlesmentioning

confidence: 96%

Poly(dopamine) grafted bio-silica composite with tetraethylenepentamine ligands for enhanced adsorption of pollutants

Arıca

Kuman

Gerçel

et al. 2019

Chemical Engineering Research and Design

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“…This nanoformulation was characterized by improved stability in water, high encapsulation efficiency of cisplatin and capability of pH-controlled cargo release. Gold nanoparticles (AuNP) were inserted into polydopamine (PDA) for modification of the surface of mesoporous silica in [213], and the fabricated composition was examined as DOX delivery system. PDA contains catechin functional groups that provide pH-sensitivity of the obtained formulation in aqueous media.…”

Section: Mesoporous Silica Nanoparticles Modified By Synthetic Polymersmentioning

confidence: 99%

Nanocarriers for Biomedicine: From Lipid Formulations to Inorganic and Hybrid Nanoparticles

Kashapov

Ibragimova

Pavlov

et al. 2021

IJMS

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Encapsulation of cargoes in nanocontainers is widely used in different fields to solve the problems of their solubility, homogeneity, stability, protection from unwanted chemical and biological destructive effects, and functional activity improvement. This approach is of special importance in biomedicine, since this makes it possible to reduce the limitations of drug delivery related to the toxicity and side effects of therapeutics, their low bioavailability and biocompatibility. This review highlights current progress in the use of lipid systems to deliver active substances to the human body. Various lipid compositions modified with amphiphilic open-chain and macrocyclic compounds, peptide molecules and alternative target ligands are discussed. Liposome modification also evolves by creating new hybrid structures consisting of organic and inorganic parts. Such nanohybrid platforms include cerasomes, which are considered as alternative nanocarriers allowing to reduce inherent limitations of lipid nanoparticles. Compositions based on mesoporous silica are beginning to acquire no less relevance due to their unique features, such as advanced porous properties, well-proven drug delivery efficiency and their versatility for creating highly efficient nanomaterials. The types of silica nanoparticles, their efficacy in biomedical applications and hybrid inorganic-polymer platforms are the subject of discussion in this review, with current challenges emphasized.

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Gold modified polydopamine coated mesoporous silica nano-structures for synergetic chemo-photothermal effect

Cited by 52 publications

References 40 publications

Syringeable Self-Organizing Gels that Trigger Gold Nanoparticle Formation for Localized Thermal Ablation

Syringeable Self-Organizing Gels that Trigger Gold Nanoparticle Formation for Localized Thermal Ablation

Poly(dopamine) grafted bio-silica composite with tetraethylenepentamine ligands for enhanced adsorption of pollutants

Nanocarriers for Biomedicine: From Lipid Formulations to Inorganic and Hybrid Nanoparticles

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