2022
DOI: 10.1007/978-981-16-4748-2_12
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Gorkha (Nepal) 2015

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Cited by 1 publication
(2 citation statements)
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“…They proposed an effect called “attinebility”, which describes the increased rebinding probability of an analyte if the neighboring receptor density is higher. This phenomenon results in a higher apparent affinity of the analyte, despite being bound to only one receptor at a time . These examples demonstrate that the original Langmuirian isotherm sometimes is unable to model biosensing data correctly and that there is a need for better models.…”
Section: Nonspecific Binding As a Bottleneck In Diagnostically Releva...mentioning
confidence: 98%
See 1 more Smart Citation
“…They proposed an effect called “attinebility”, which describes the increased rebinding probability of an analyte if the neighboring receptor density is higher. This phenomenon results in a higher apparent affinity of the analyte, despite being bound to only one receptor at a time . These examples demonstrate that the original Langmuirian isotherm sometimes is unable to model biosensing data correctly and that there is a need for better models.…”
Section: Nonspecific Binding As a Bottleneck In Diagnostically Releva...mentioning
confidence: 98%
“…Several groups have observed non-Langmuirian receptor density-dependent DNA–DNA interactions. , The observed effect is non-Langmuirian because the fractional occupancy of DNA was increased by increasing the receptor DNA density. Ozer et al accounted for this effect by implementing a cooperative model, which combines the Langmuirian specific binding with a non-Langmuirian receptor density-dependent cooperative NSB .…”
Section: Nonspecific Binding As a Bottleneck In Diagnostically Releva...mentioning
confidence: 99%