Graded Compression and Power Doppler Ultrasonography Versus Endoscopy to Assess Paediatric Crohn Disease Activity Pre‐ and Posttreatment

Abstract

Results obtained using power Doppler ultrasonography and endoscopy showed statistically significant correlations. Power Doppler sonography, in the hands of an experienced examiner, can be used for follow-up assessment of disease activity in children with Crohn disease.

Bowel Ultrasonography in the Management of Crohnʼs Disease. A Review with Recommendations of an International Panel of Experts

“…The utility of bowel US for assessing drug response has been compared with ileocolonoscopy only in 3 studies in which concordance was high (weighted k between 0.63 and 0.76). 80,82,86 Two studies showed no changes in ultrasongraphic parameters before and after therapy. 81,87 One study demonstrated variations of a combination of sonographic parameters (sonographic lesion index for CD) only in patients with clinical response to anti-tumor necrosis factor a treatments induction.…”

“…Nine studies including 265 patients with CD, have explored the evolution of sonographic parameters of inflammation over time during medical therapy [80][81][82][83][84][85][86][87][88] (see Table 11, Supplemental Digital Content 5, http://links.lww.com/IBD/B238). The utility of bowel US for assessing drug response has been compared with ileocolonoscopy only in 3 studies in which concordance was high (weighted k between 0.63 and 0.76).…”

Pediatric Small Bowel Crohn Disease: Correlation of US and MR Enterography

“…More recently, several authors have suggested that ultrasonography (US) can be used for screening and follow-up of small bowel Crohn disease in children (6)(7)(8)(9)(10)(11). Technologic advances in US have allowed improved visualization of the small bowel and mesentery, especially in the pediatric population.…”

“…Technologic advances in US have allowed improved visualization of the small bowel and mesentery, especially in the pediatric population. One pediatric study ing one or more high-frequency linear transducers (8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18), convex transducers with lower frequencies may be useful for visualizing bowel loops located deep within the abdomen or pelvis and for examining obese children. Graded compression of the anterior abdominal wall with the US transducer and manual posterior compression with the nonscanning hand can be used to displace or efface normal overlying air and fluid-filled bowel loops and bring abnormal bowel segments closer to the transducer for improved image quality (10,14).…”

Radiation exposure in children with inflammatory bowel disease

“…Multiple studies, including a pediatric study, have used ultrasound to evaluate Crohn's disease and to monitor disease [26][27][28]. The results of these studies suggest that ultrasound can detect ileal disease and can be used to monitor improvement in disease, if there is an experience and expertise in ultrasound at an institution.…”