Grafting on nanoparticles: is solid-state NMR a convenient tool of investigation?

Abstract

The recent developments of Solid-State NMR in both theoretical and experimental fields are exponential. Multidimensional correlation techniques based on the dipolar interaction (D) and the scalar interaction (J) allow the fine description of hybrid materials and nanomaterials. The organic (bioorganic)/ inorganic interfaces are difficult to characterize by standard techniques, whereas solid-state NMR can be applied successfully to this particular task. 1 H solid-state NMR spectroscopy will be introduced in the frame of the study of hybrids and nanomaterials. High resolution 1 H NMR in solids remains a huge challenge in terms of theoretical understanding and technology. Cross-polarization (CP) experiments involving the heteronuclear dipolar interaction (and leading to the estimation of internuclear distances) will be presented in the frame of silicophosphates, which can be considered as precursors for biocompatible materials. CP experiments allow to estimate the spatial connectivities between the various components of a given material. MAS-J experiments (INEPT, HMQC) dealing with through bonds chemical connectivities will be presented as well. The potential offered by such techniques will be applied to the spectroscopic characterization of chemical grafting at the surface of nanoparticles (SiO 2 , TiO 2 …).

Conjugates of Nanomaterials with Phthalocyanines

“…chemical grafting at the surface of Si0 2 nanoparticles [70], and the doping of lanthanum fluoride nanoparticles [71]. chemical grafting at the surface of Si0 2 nanoparticles [70], and the doping of lanthanum fluoride nanoparticles [71].…”