Granulocytic Sarcoma (Chloroma) Initially Seen as Acute Mastoiditis

Thompson, David H.; Ross, Denise G.; Reid, James W.

doi:10.1001/archotol.1982.00790540060018

Cited by 13 publications

(10 citation statements)

References 16 publications

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“…There are very few published case reports of myeloid sarcoma involving the temporal bone. Most of them involved the mastoid, and the patients presented with symptoms related to mastoid involvement (2, 4, 9-13). The predominance of the tumor in the mastoid cavity can be explained by that fact that the latter is more vulnerable to harboring a mass than the hard petrous bone.…”

Section: Discussionmentioning

confidence: 99%

Temporal Bone Myeloid Sarcoma

Chang

Kim

Jun

et al. 2009

Clin Exp Otorhinolaryngol

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Myeloid sarcoma is a rare condition that's caused by the aggregation of immature myeloid cells in leukemic patients. Myeloid sarcoma occurring in the temporal bone more frequently involves the mastoid bone than is the case for metastatic lesions arising from non-systemic malignancies. The disease is difficult to diagnose when it presents with symptoms that mimic otomastoiditis. However, an early diagnosis is important in order to achieve complete remission of the disease. Magnetic resonance imaging of the temporal bone is useful for making the diagnosis of myeloid sarcoma, and especially to evaluate the extent of disease. High-dose radio- or chemotherapies are the first-line approaches and possibly the only approaches to achieve complete remission and to cure the disease. With the aim of improving our understanding of myeloid sarcoma in the temporal bone, the present report describes our experience with 5 such cases and we compare the clinical features of these 5 patients with those clinical features of patients who have metastatic lesions.

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Section: Discussionmentioning

confidence: 99%

Temporal Bone Myeloid Sarcoma

Chang

Kim

Jun

et al. 2009

Clin Exp Otorhinolaryngol

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“…Erkrankungen des Blutes und des hämatopoetischen Systems lassen sich heute in die folgenden 4 Subkategorien gruppieren [125,126] [131]. Die Diagnostik umfasst eine CT, welche knöcherne Destruktionen zeigen kann, und eine Magnetresonanztomografie (MRT), welche eine Signalanreicherung in den entsprechenden Läsionen nach Kontrastmittelgabe aufweist.…”

Section: Neoplasien Des Hämatopoetischen Systemsunclassified

“…Symptoms, that are primarily due to growth, include aural fullness, otalgia, otorrhoea and facial paresis. The symptoms resemble those of acute otitis media [131]. Diagnosis includes CT, that may show bony destructions, and magnetic resonance imaging (MRI), that shows a signal enhancement in the corresponding lesions after contrast administration.…”

Section: Leukaemia Of the Temporal Bonementioning

confidence: 99%

Seltene Erkrankungen des Mittelohres und der lateralen Schädelbasis

Weiss

2021

Laryngorhinootologie

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ZusammenfassungOtalgie, Otorrhoe, Tinnitus und Hörminderung zählen zu den häufigsten ohrbezogenen Symptomen, die zum Aufsuchen eines Hals-Nasen-Ohrenarztes führen. Weiterhin spielen Gleichgewichtsstörungen und Affektionen der Hirnnervenfunktion für eine Konsultation eine Rolle. In großen akademischen Zentren, aber auch in der HNO-ärztlichen Grundversorgung kommt der Erkennung von seltenen Erkrankungen des Mittelohres und der lateralen Schädelbasis eine zentrale Rolle zu, da sie häufig eine interdisziplinäre Zusammenarbeit erfordern um die korrekte Diagnose zu stellen und eine adäquate Behandlung zu initiieren. Die folgende Arbeit gibt einerseits eine Übersicht über seltene Formen von osteologischen, neoplastischen, hämatologischen, autoimmunologischen und infektiologischen Erkrankungen sowie Fehlbildungen, die sich im Mittelohr und der lateralen Schädelbasis manifestieren können, andererseits soll ein Überblick über internistische Erkrankungen gegeben werden, deren Manifestation im Mittelohr selten ist. Die Kenntnis von seltenen Erkrankungen des Mittelohrs und der Schädelbasis ist für die Qualitätssicherung in der Patientenversorgung und insbesondere auch bei entsprechenden chirurgischen Maßnahmen wesentlich. Insbesondere bei untypischen, komplizierten und langwierigeren Krankheitsverläufen muss an seltene Differenzialdiagnosen gedacht werden.

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“…Fourteen studies comprised an additional 16 adults with diseases mimicking AM (Table 3). 8,17,[28][29][30][31][32][33][34][35][36][37][38][39][40] Two studies included children and adults. 8,17 Age ranged from 18 to 88 years with a male predominance (9 males, 6 females, 1 not reported).…”

Section: Mastoiditis Mimickersmentioning

confidence: 99%

“…Six studies conducted audiometric testing in adults. Three adults experienced conductive hearing loss (LCH 17,33 and SCC 38 ), 1 experienced mixed hearing loss (aneurysmal bone cyst 29 ), and the remaining 2 were unspecified. No study indicated the degree of hearing loss.…”

Section: Audiometric Findingsmentioning

confidence: 99%

A Review of Noninfectious Diseases Masquerading as Acute Mastoiditis

Wong

Arrighi‐Allisan

Fan

et al. 2021

Otolaryngol.--head neck surg.

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Objective Acute mastoiditis is commonly attributed to infection. Rarely do clinicians encounter cases that do not respond to traditional antibiotics or surgical management. The goal of this study was to systematically review the literature to characterize diseases masquerading as acute infectious mastoiditis. Data Sources PubMed, Embase, and Scopus. Review Methods A systematic review was performed to identify all publications that reported on diseases with presentations mimicking acute mastoiditis, defined as postauricular redness, swelling, and tenderness. We included clinical prospective studies, retrospective studies, and case series/reports. Exclusion criteria included non-English articles, letters/commentaries, abstracts, and review articles. Results Out of 3339 results, 35 studies met final inclusion criteria. In children, 11 diseases were reported to mimic mastoiditis, including solid tumors, hematologic diseases, and autoimmune/inflammatory diseases. The most common disease in children was Langerhans cell histiocytosis, followed by rhabdomyosarcoma and acute myelogenous leukemia. In adults, 8 additional diseases were reported. The most common disease in adults was squamous cell carcinoma, followed by nasopharyngeal carcinoma and Langerhans cell histiocytosis. Presenting symptoms are reviewed, as well as characteristic radiographic, laboratory, and intraoperative features that may assist with diagnosis. A diagnostic algorithm for atypical cases of acute mastoiditis is proposed. Conclusion A small but significant group of diseases in children and adults can mimic acute mastoiditis. In such cases, history and examination alone may be insufficient to reach a diagnosis, and further investigation may be necessary. Otolaryngologists should always be mindful of the possibility that noninfectious pathologies may present with a constellation of symptoms similar to mastoiditis.

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Granulocytic Sarcoma (Chloroma) Initially Seen as Acute Mastoiditis

Cited by 13 publications

References 16 publications

Temporal Bone Myeloid Sarcoma

Temporal Bone Myeloid Sarcoma

Seltene Erkrankungen des Mittelohres und der lateralen Schädelbasis

A Review of Noninfectious Diseases Masquerading as Acute Mastoiditis

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