2017
DOI: 10.1039/c6ra27887f
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Graphene oxide and adenosine triphosphate as a source for functionalized carbon dots with applications in pH-triggered drug delivery and cell imaging

Abstract: A folate-functionalized carbon dot-based nanocarrier system has been successfully synthesized for cancer cell targeted drug delivery.

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Cited by 27 publications
(18 citation statements)
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“…Another quantitative spectroscopic technique, XPS was also used to measure the elemental composition and the nature of functional groups present in the surface of the ChOx‐gRGO‐PPy composite. The binding energy (BE) values were chosen based on published works . However there might be slight changes in the BE due to the presence of neighboring groups.…”
Section: Resultsmentioning
confidence: 99%
“…Another quantitative spectroscopic technique, XPS was also used to measure the elemental composition and the nature of functional groups present in the surface of the ChOx‐gRGO‐PPy composite. The binding energy (BE) values were chosen based on published works . However there might be slight changes in the BE due to the presence of neighboring groups.…”
Section: Resultsmentioning
confidence: 99%
“…6,7 PTT converts absorbed light into thermal energy and generates local hyperthermia in the tumor mass to ablate cancer cells without causing damage to surrounding normal tissue. [8][9][10] Photodynamic therapy (PDT), a minimally invasive and high-efficiency anticancer approach, has recently received extensive research attention. PDT involves photosensitizers that absorb light and further transfer energy to oxygen in the surrounding tissue.…”
Section: Introductionmentioning
confidence: 99%
“…[16] Recently,p hotothermal therapy (PTT) in synergy with chemotherapy or other therapeutic modalities have been extensively investigated by numerous researchers. [17] Killing cancer cells via heat generated by laser irradiation of NIR light-absorbing agents instead of simple traditional heatinga pproachh as drew great attention. Moreover,s uch temperature has been provedt ok ill cancer cells via hyperthermia-induced cell necrosis and am ild photothermal heating (43-45 8C).…”
Section: Introductionmentioning
confidence: 99%
“…[18] Additionally, integrating an umber of imaging methods such as fluorescent imaginga nd magnetic resonance imaging (MRI) with imagingguided therapy makesi tpossible to monitor the behaviors of nanocarriers (NCs) and then to optimize the therapeutic windows, which would then be useful to accurately personalize therapiesw ith furtheri mproved therapeutic effects andr educed side effects. [17] Many photothermal agents for building NIR-triggeredn anodrug carriers have been extensivelye xplored over recent years. Despite that large number of photothermala gents (e.g.,C uS NPs, [19] MoS 2 NPs, [20] polymers NPs, [21] Au NPs, [22] Cu 2Àx Se NPs, [23] Pd-based nanosheets, [24] Ge NPs, [25] and Sb NPs [26] )c an be used for buildingN IR-triggered nanodrug carriers, little is known about their potential long-term toxicity, which hampers their clinical translation.…”
Section: Introductionmentioning
confidence: 99%