Graphene Oxide Quantum Dots Derived from Coal for Bioimaging: Facile and Green Approach

Kang, Sung-Myung; Kim, Kang Min; Jung, Kyunghwan; Son, Yong; Mhin, Sungwook; Ryu, Jeong Ho; Shim, Kwang Bo; Lee, Byoung-Soo; Han, Houde; Song, Taeseup

doi:10.1038/s41598-018-37479-6

Cited by 75 publications

(58 citation statements)

References 33 publications

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“…Kang et al transformed Earth's rich resources and low-cost coal into CQDs within 5 minutes through a simple, lowcost, environmentally friendly liquid pulse laser ablation method. 63 CQDs prepared by laser ablation have good water dispersibility and strong fluorescence properties, but their wide application is hindered by low yield, uneven particle size and complex operation.…”

Section: "Top-down" Methodsmentioning

confidence: 99%

Recent Advances in Functional Carbon Quantum Dots for Antitumour

Cai¹,

Xiao²,

Liu³

et al. 2021

IJN

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Carbon quantum dots (CQDs) are an emerging class of quasi-zero-dimensional photoluminescent nanomaterials with particle sizes less than 10 nm. Owing to their favourable water dispersion, strong chemical inertia, stable optical performance, and good biocompatibility, CQDs have become prominent in biomedical fields. CQDs can be fabricated by "top-down" and "bottom-up" methods, both of which involve oxidation, carbonization, pyrolysis and polymerization. The functions of CQDs include biological imaging, biosensing, drug delivery, gene carrying, antimicrobial performance, photothermal ablation and so on, which enable them to be utilized in antitumour applications. The purpose of this review is to summarize the research progress of CQDs in antitumour applications from preparation and characterization to application prospects. Furthermore, the challenges and opportunities of CQDs are discussed along with future perspectives for precise individual therapy of tumours.

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Section: "Top-down" Methodsmentioning

confidence: 99%

Recent Advances in Functional Carbon Quantum Dots for Antitumour

Cai¹,

Xiao²,

Liu³

et al. 2021

IJN

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“…The top-down synthesis of GQDs implies the oxidative cleavage of various carbon materials, such as graphite [ 98 ], carbon nanotubes [ 99 ], carbon nanofibers [ 100 ], fullerenes [ 101 ], graphene oxide (GO) [ 102 ], carbon black [ 103 ], and even coal [ 104 , 105 ], to obtain quantum dots. The general mechanism is based on the oxidation and exfoliation of bulk carbon materials using different chemical and physical agents, such as strong acids, high temperature and pressure, an electric current, microwave irradiation, ultrasonic waves, a laser beam, and others [ 106 ].…”

Section: Graphene Quantum Dots Synthetic Strategiesmentioning

confidence: 99%

Shedding Light on Graphene Quantum Dots: Key Synthetic Strategies, Characterization Tools, and Cutting-Edge Applications

2021

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During the last 20 years, the scientific community has shown growing interest towards carbonaceous nanomaterials due to their appealing mechanical, thermal, and optical features, depending on the specific nanoforms. Among these, graphene quantum dots (GQDs) recently emerged as one of the most promising nanomaterials due to their outstanding electrical properties, chemical stability, and intense and tunable photoluminescence, as it is witnessed by a booming number of reported applications, ranging from the biological field to the photovoltaic market. To date, a plethora of synthetic protocols have been investigated to modulate the portfolio of features that GQDs possess and to facilitate the use of these materials for target applications. Considering the number of publications and the rapid evolution of this flourishing field of research, this review aims at providing a broad overview of the most widely established synthetic protocols and offering a detailed review of some specific applications that are attracting researchers’ interest.

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“…Environmentally-friendly synthetic routes to obtain high-quality and high-performance CDs are still need of the hour to address. Therefore, from environmental and sustainable development perspective, green methods of synthesis are always preferred over non-green methods [ 26 , 27 ]. The utilization of biomass as precursor is a welcome step since it is inexpensive and renewable.…”

Section: Introductionmentioning

confidence: 99%