Green analytical methodologies to determine personal care products in solid environmental matrices: Soils, sediments, sludge and biota ˗ A review

Celeiro, María; Llompart, Marı́a; Dagnac, Thierry

doi:10.1016/j.sampre.2022.100013

Cited by 8 publications

(3 citation statements)

References 106 publications

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“…Pharmaceutical products generally consist of biologically active organic compounds including but not limited to antibiotics, antidepressants, stimulants, X-ray contrast media drugs, anti-inflammatory, lipid regulators, β-blockers, antihypertensive compounds, and illicit/recreational drugs (Richmond et al, 2017 ; Yang, et al, 2017 ). Personal care products (PCPs) include chemical compounds found in household products, cosmetics, and health care products, such as sunscreen agents, antifungals, insect repellents, and antibacterial agents (i.e., triclosan and triclocarban; Celeiro et al, 2022 ). PPCPs are recognized as chemicals of emerging concern (CECs) due to their increased use in human and veterinary medicine, pseudo-persistence (e.g., widespread usage and continuous release/loading, resulting in measurable levels in the environment; Dehm et al, 2021 ), and frequent detection in industrial and municipal wastewater treatment systems, soil, sediment, drinking water, ground water, and surface water (Zakari-Jiya et al, 2022 ).…”

Section: Introductionmentioning

confidence: 99%

An assessment and characterization of pharmaceuticals and personal care products (PPCPs) within the Great Lakes Basin: Mussel Watch Program (2013–2018)

M. A.,

K.,

et al. 2024

Environ Monit Assess

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Defining the environmental occurrence and distribution of chemicals of emerging concern (CECs), including pharmaceuticals and personal care products (PPCPs) in coastal aquatic systems, is often difficult and complex. In this study, 70 compounds representing several classes of pharmaceuticals, including antibiotics, anti-inflammatories, insect repellant, antibacterial, antidepressants, chemotherapy drugs, and X-ray contrast media compounds, were found in dreissenid mussel (zebra/quagga; Dreissena spp.) tissue samples. Overall concentration and detection frequencies varied significantly among sampling locations, site land-use categories, and sites sampled proximate and downstream of point source discharge. Verapamil, triclocarban, etoposide, citalopram, diphenhydramine, sertraline, amitriptyline, and DEET (N,N-diethyl-meta-toluamide) comprised the most ubiquitous PPCPs (> 50%) detected in dreissenid mussels. Among those compounds quantified in mussel tissue, sertraline, metformin, methylprednisolone, hydrocortisone, 1,7-dimethylxanthine, theophylline, zidovudine, prednisone, clonidine, 2-hydroxy-ibuprofen, iopamidol, and melphalan were detected at concentrations up to 475 ng/g (wet weight). Antihypertensives, antibiotics, and antidepressants accounted for the majority of the compounds quantified in mussel tissue. The results showed that PPCPs quantified in dreissenid mussels are occurring as complex mixtures, with 4 to 28 compounds detected at one or more sampling locations. The magnitude and composition of PPCPs detected were highest for sites not influenced by either WWTP or CSO discharge (i.e., non-WWTPs), strongly supporting non-point sources as important drivers and pathways for PPCPs detected in this study. As these compounds are detected at inshore and offshore locations, the findings of this study indicate that their persistence and potential risks are largely unknown, thus warranting further assessment and prioritization of these emerging contaminants in the Great Lakes Basin. Graphical Abstract

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Section: Introductionmentioning

confidence: 99%

An assessment and characterization of pharmaceuticals and personal care products (PPCPs) within the Great Lakes Basin: Mussel Watch Program (2013–2018)

M. A.,

K.,

et al. 2024

Environ Monit Assess

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“…As a result, the efficiency of extraction depends on both the method of energy transfer and the amount of energy provided. Microwave- and ultrasound-assisted extractions (MAE and UAE), as well as accelerated solvent extraction (ASE), are among the most popular approaches to recover CECs from abiotic and biotic matrices . These systems allow the simultaneous extraction of multiple samples at high temperature (MAE, UAE, and ASE) and/or pressure (MAE and ASE).…”

Section: Introductionmentioning

confidence: 99%

“…Microwave-and ultrasound-assisted extractions (MAE and UAE), as well as accelerated solvent extraction (ASE), are among the most popular approaches to recover CECs from abiotic and biotic matrices. 8 These systems allow the simultaneous extraction of multiple samples at high temperature (MAE, UAE, and ASE) and/or pressure (MAE and ASE). However, none of these systems can be connected directly to a liquid chromatograph, making it impossible to automate the entire analysis chain of solid samples and thus influencing the green character of these extraction approaches.…”

Section: ■ Introductionmentioning

confidence: 99%

A Novel Apparatus for the Fully Automated Extraction and Online Liquid Chromatographic Analysis of Solid Environmental Samples: Application to the Pressurized Hot Water Extraction of Pharmaceuticals in Soil

Bonaccorso,

Renai,

Checchini

et al. 2024

Anal. Chem.

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A new self-assembled apparatus for the extraction of solid samples was designed and implemented to perform a recirculated pressurized hot water extraction (R-PHWE) directly coupled to liquid chromatography-tandem mass spectrometry. To investigate the potential of this new extraction apparatus, 34 target pharmaceutical compounds were analyzed in loam, silt-loam, and silty-clay-loam soils. The target analytes were characterized by heterogeneous physicochemical properties (e.g., −1.60 ≤ log D ≤ 5.91 at pH = 7.2, i.e., at the mean pH values of the three soils). Design of experiments (DoE) was used to identify the best extraction conditions for the target analytes by studying temperature, pressure, and number of extraction cycles. The results of DoE optimization pointed out the significant influence of the number of cycles on recovery. The application of DoE set point to the three reference soils provided recoveries ≥60% for 21−25 out the 34 target analytes, depending on soil. Good recovery precision (<25%) and moderate suppressive matrix effect (≤40%) were found for most target analytes, regardless of the soil considered. The optimized R-PHWE procedure evidenced statistically higher recoveries for 16 out of 34 target analytes when compared to conventional off-line dynamic PHWE.

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Analytical Methods to Analyze Fragrances in Environmental Matrices

Llompart

Celeiro

2023

The Handbook of Environmental Chemistry

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Green analytical methodologies to determine personal care products in solid environmental matrices: Soils, sediments, sludge and biota ˗ A review

Cited by 8 publications

References 106 publications

An assessment and characterization of pharmaceuticals and personal care products (PPCPs) within the Great Lakes Basin: Mussel Watch Program (2013–2018)

An assessment and characterization of pharmaceuticals and personal care products (PPCPs) within the Great Lakes Basin: Mussel Watch Program (2013–2018)

A Novel Apparatus for the Fully Automated Extraction and Online Liquid Chromatographic Analysis of Solid Environmental Samples: Application to the Pressurized Hot Water Extraction of Pharmaceuticals in Soil

Analytical Methods to Analyze Fragrances in Environmental Matrices

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