Green and recyclable sulfonated graphene and graphene oxide nanosheet catalysts for the syntheses of 3,4-dihydropyrimidinones

Vessally, Esmail; Hassanpour, Akbar; Hosseinzadeh‐Khanmiri, Rahim; Babazadeh, Mirzaagha; Abolhasani, Jafar

doi:10.1007/s00706-016-1762-2

“…In comparison to graphene oxide, sulfonated graphene was found to be a more effective catalyst. [ 44 ] Mobinikhaledi et al developed a highly efficient heterogeneous magnetically recyclable nanocatalyst, Fe 3 O 4 /SiO 2 ‐NH‐ligand‐Bi(III) complex for the preparation of 2‐oxo/thioxo‐1,2,3,4‐tetrahydropyrimidine derivatives. This method has several advantages such as excellent yield of product, clean reaction conditions, operational simplicity, shorter reaction time, and environmental degradation to a minimum.…”

Section: Synthetic Routesmentioning

confidence: 99%

Catalytic role in Biginelli reaction: Synthesis and biological property studies of 2‐oxo/thioxo‐1,2,3,4‐tetrahydropyrimidines

Kamat

¹

,

Reddy

²

,

Kumar

³

2023

Archiv der Pharmazie

3

0

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The Biginelli reaction has received significant consideration in recent years due to its easily accessible aldehyde, urea/thiourea, and active methylene compounds. When it comes to pharmacological applications, the Biginelli reaction end‐products, the 2‐oxo‐1,2,3,4‐tetrahydropyrimidines, are vital in pharmacological applications. Due to the ease of carrying out the Biginelli reaction, it offers a number of exciting prospects in various fields. Catalysts, however, play an essential role in Biginelli's reaction. In the absence of a catalyst, it is difficult to form products with a good yield. Many catalysts have been used in search of efficientmethodologies, including biocatalysts, Brønsted/Lewis acids, heterogeneous catalysts, organocatalysts, and so on. Nanocatalysts are currently being applied in the Biginelli reaction to improve the environmental profile as well as speed up the reaction process. This review describes the catalytic role in the Biginelli reaction and pharmacological application of 2‐oxo/thioxo‐1,2,3,4‐tetrahydropyrimidines. This study provides information that will facilitate the development of newer catalytic methods for the Biginelli reaction, by academics as well as industrialists. It also offers a broad scope for drug design strategies, which may enable the development of novel and highly effective bioactive molecules.

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“…Among these nano catalysts, nano structured compounds based on graghene, such as graphene oxide nanosheet, [46] BiFeO 3 nanowire-Reduced Graphene Oxide, [47] clay -graphene oxide nano composite [48], Phosphate functionalized graphene oxide [49] and Fe 3 O 4 -GO-NH 2 [50] developed for organic synthesis transformations like these two condensation.…”

Section: Introductionmentioning

confidence: 99%

“…Also some reaction protocols have applied for the synthesis of tetrahydro-4H-chromenes with the use of nano catalysts such as 4-Dialkylaminopyridine modi ed magnetic nanoparticles, [40]silica-supported magnetic nanocatalyst, [41] [45]. Among these nano catalysts, nano structured compounds based on graghene, such as graphene oxide nanosheet, [46] BiFeO 3 nanowire-Reduced Graphene Oxide, [47] clay -graphene oxide nano composite [48], Phosphate functionalized graphene oxide [49] and Fe 3 O 4 -GO-NH 2 [50] developed for organic synthesis transformations like these two condensation.…”

Section: Introductionmentioning

confidence: 99%

Ag2O/GO/TiO2 Composite Nanostructure: an efficient heterogeneous catalyst for one pot synthesis of Bis (dihydropyrimidinone) and tetrahydro-4H-chromenes derivatives

Zadeh

¹

,

Mohammadi

²

,

Raeiatzadeh

³

et al. 2021

Preprint

0

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The simple and efficient synthesis reaction was used for preparing Bis (dihydropyrimidinone) derivatives through Biginelli condensation reaction of terephthalic aldehyde, 1, 3-dicarbonyl compounds and (thio) urea or guanidine and tetrahydro-4H-chromenes via one pot condensation of aromatic aldehydes, malononitrile and dimedone with Ag2O/GO/TiO2 composite nanostructures as a catalyst. The structural functionalities and morphological observations of catalyst were obtained using characterization techniques of field emission scanning electron microscopy (FESEM), X-ray diffraction (XRD), Fourier transfer infrared (FT-IR) spectroscopy and transmission electron microscope (TEM). The structures of Bis (dihydropyrimidinone) and tetrahydro-4H-chromenes confirmed by FT- IR, NMR and mass spectroscopy. Excellent yields of the products, simple reaction process and simple work-up are attractive features of these effective synthesis methods.

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“…Among these nano catalysts, nano structured compounds based on graghene, such as graphene oxide nanosheet, [46] BiFeO3 nanowire-Reduced Graphene Oxide, [47] claygraphene oxide nano composite [48], Phosphate functionalized graphene oxide [49] and Fe3O4-GO-NH2 [50] developed for organic synthesis transformations like these two condensation.…”

Section: Introductionmentioning

confidence: 99%

Ag2O/GO/TiO2 Composite Nanostructure: An Efficient Heterogeneous Catalyst for one Pot Synthesis of Bis (Dihydropyrimidinone) and Tetrahydro-4H-chromenes Derivatives

Zadeh

¹

,

Mohammadi

²

,

Rayatzadeh

³

et al. 2020

Preprint

0

View full text Add to dashboard Cite

The simple and efficient synthesis reaction was used for preparing Bis (dihydropyrimidinone) derivatives through Biginelli condensation reaction of terephthalic aldehyde, 1, 3-dicarbonyl compounds and (thio) urea or guanidine and tetrahydro-4H-chromenes via one pot condensation of aromatic aldehydes, malononitrile and dimedone with Ag2O/GO/TiO2 composite nanostructures as a catalyst. The structural functionalities and morphological observations of catalyst were obtained using characterization techniques of field emission scanning electron microscopy (FESEM), X-ray diffraction (XRD), Fourier transfer infrared (FT-IR) spectroscopy and transmission electron microscope (TEM). The structures of Bis (dihydropyrimidinone) and tetrahydro-4H-chromenes confirmed by FT- IR, NMR and mass spectroscopy. Excellent yields of the products, simple reaction process and simple work-up are attractive features of these effective synthesis methods.

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Green and recyclable sulfonated graphene and graphene oxide nanosheet catalysts for the syntheses of 3,4-dihydropyrimidinones

Cited by 24 publications

References 42 publications

Catalytic role in Biginelli reaction: Synthesis and biological property studies of 2‐oxo/thioxo‐1,2,3,4‐tetrahydropyrimidines

Catalytic role in Biginelli reaction: Synthesis and biological property studies of 2‐oxo/thioxo‐1,2,3,4‐tetrahydropyrimidines

Ag2O/GO/TiO2 Composite Nanostructure: an efficient heterogeneous catalyst for one pot synthesis of Bis (dihydropyrimidinone) and tetrahydro-4H-chromenes derivatives

Ag2O/GO/TiO2 Composite Nanostructure: An Efficient Heterogeneous Catalyst for one Pot Synthesis of Bis (Dihydropyrimidinone) and Tetrahydro-4H-chromenes Derivatives

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