Green Extraction Techniques for Phytoconstituents from Natural Products

Raj, Bincy; John, Swarbrooke; Chandrakala, V.; Kumari, Gajula Harini

doi:10.5772/intechopen.105088

Cited by 3 publications

(4 citation statements)

References 47 publications

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“…[48] Sustainable solvents include (1) ionic liquids -IL, (2) water -W, (3) supercritical carbon dioxide -SCÀ CO 2 , (4) deep eutectic solvents -DES, (5) natural DES -NADE, and (6) biosolvents -BS (such as ethyl lactate, methyl acetate, ethyl acetate. [46,49] Several review articles discuss these alternative methodologies, [46,[49][50][51] also giving examples of their use in the extraction of natural products, such as fungal pigments, phytoconstituents, and caffeine extraction. [50,52] Step 4 encompasses the chemical analysis of the obtained extracts.…”

Section: Culture Media and Fungal Metabolomementioning

confidence: 99%

“…[46,49] Several review articles discuss these alternative methodologies, [46,[49][50][51] also giving examples of their use in the extraction of natural products, such as fungal pigments, phytoconstituents, and caffeine extraction. [50,52] Step 4 encompasses the chemical analysis of the obtained extracts. Techniques such as liquid chromatography with various detectors (HPLC-DAD, LC-MS/MS, UPLC-HRMS, UPLC-HRMS-MS), gas chromatography coupled with mass spectrometry (GC-MS), and nuclear magnetic resonance (NMR) are employed.…”

Section: Culture Media and Fungal Metabolomementioning

confidence: 99%

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Exploring Culture Media Diversity to Produce Fungal Secondary Metabolites and Cyborg Cells

Geris,

Teles de Jesus,

Ferreira da Silva

et al. 2024

Chemistry & Biodiversity

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Fungi are microorganisms of significant biotechnological importance due to their ability to provide food and produce several value‐added secondary metabolites and enzymes. Its products move billions of dollars in the pharmaceutical, cosmetics, and additives sectors. These microorganisms also play a notable role in bionanotechnology, leading to the production of hybrid biological‐inorganic materials (such as cyborg cells) and the use of their enzyme complex in the biosynthesis of nanoparticles. In this sense, optimizing the fungal growth process is necessary, with selecting the cultivation medium as one of the essential factors for the microorganism to reach its maximum metabolic expression. The culture medium's composition can also impact the nanomaterial's stability and prevent the incorporation of nanoparticles into fungal cells. Therefore, our main objectives are the following: (1) compile and discuss the most commonly employed culture media for the production of fungal secondary metabolites and the formation of cyborg cells, accompanied by preparation methods; (2) provide a six‐step guide to investigating the fungal metabolomic profile and (3) discuss the main procedures of microbial cultivation to produce fungal cyborg cells.

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Section: Culture Media and Fungal Metabolomementioning

confidence: 99%

Section: Culture Media and Fungal Metabolomementioning

confidence: 99%

Exploring Culture Media Diversity to Produce Fungal Secondary Metabolites and Cyborg Cells

Geris,

Teles de Jesus,

Ferreira da Silva

et al. 2024

Chemistry & Biodiversity

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“…A modern research area is the development of green extraction methods, which aim at improving the performance and environmental sustainability of extracting natural products. Green extraction methods are characterized by low energy consumption, high selectivity and efficiency, minimal use of harmful solvents, and safe and high-quality outcomes [20]. Advantages include minimized solvent consumption, absence of hazardous substances, shortened extraction durations, and low energy consumption [21][22][23].…”

Section: Introductionmentioning

confidence: 99%

Seeking Optimal Extraction Method for Augmenting Hibiscus sabdariffa Bioactive Compounds and Antioxidant Activity

Kourelatou,

Chatzimitakos,

Athanasiadis

et al. 2024

Processes

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The dried flowers of Hibiscus sabdariffa (HS), available worldwide, have various applications in both non-medicinal and medicinal fields. The growing global interest in the health benefits of HS is linked to its potential prevention or management of non-communicable diseases. The aim of this research was to find the optimal extraction method that ensures the maximum yield of multiple beneficial bioactive components, such as polyphenols, anthocyanins, vitamin C, β-carotene, antioxidant activity, free radical scavenging activity DPPH and ferric reducing antioxidant power (FRAP). To this end, stirring, pulsed electric field, and ultrasound-assisted extraction were evaluated, either alone or in combination. Under optimized extraction conditions, the obtained extract exhibited an elevated total polyphenol content (37.82 mg of gallic acid equivalents/g dry weight (dw)), total anthocyanin content (610.42 μg of cyanidin equivalents/g dw), total carotenoids content (921.84 μg of β-carotene equivalents/g dw), and ascorbic acid content (507.44 mg/100 g dw). Remarkably, the extracts exhibited strong antioxidant properties (487.51 μmol of ascorbic acid equivalents (AAE)/g dw and 243.42 μmol AAE/g dw as evidenced by FRAP and DPPH assays, respectively). This research advances the parameters that should be employed to produce the optimal and nutritionally enhanced HS flower extracts, that can be used in the commercial sector.

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“…They include ultrasound-assisted extraction, microwave-assisted extraction, high-pressure, subcritical, and supercritical water extraction, pressurized liquid extraction, negative pressure cavitations-assisted extraction, enzyme-assisted extraction, pulsed electric field-assisted extraction, and accelerated solvent extraction. The goal is to limit, lower, or exclude the use of solvent, minimize the use of energy, generate fewer by-products and waste streams, shorten the extraction time, and improve natural ingredient recovery [ 14 ].…”

Section: Introductionmentioning

confidence: 99%

The Effect of Green Extraction Technologies on the Chemical Composition of Medicinal Chaga Mushroom Extracts

Lazić,

Klaus,

Kozarski

et al. 2024

JoF

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The mushroom industry should implement green extraction technologies; however, there is not enough information on the differences between these techniques expressed as the chemical composition of the resulting extract. In this study, selected types of green extraction techniques (GETs) were used on Chaga (Inonotus obliquus) (Fr.) Pilát from Serbia (IS) and Mongolia (IM) to examine the differences that would enable the composition-based technology choices in the mushroom supplement industry. Subcritical water extraction (SWE), microwave-assisted (MW) extraction, and ultrasonic-assisted extraction (VAE) were used to prepare the extracts. SWE was performed at two different temperatures (120 and 200 °C), while 96% ethanol, 50% ethanol, and water were used for MW and VAE. The yield, the content of total phenols, total proteins, and carbohydrates, qualitative and quantitative analysis of phenolic compounds, carbohydrates, including α- and β- and total glucans, and fatty acids, were determined in the obtained extracts. SWE resulted in a significantly higher yield, total polysaccharide, and glucan content than any other technique. Glucose was the most dominant monosaccharide in the SWE samples, especially those extracted at 200 °C. The MW 50% EtOH extracts showed the highest yield of total phenols. Among the tested phenolic compounds, chlorogenic acid was the most dominant. SWE can be recommended as the most efficient method for extracting commercially important compounds, especially glucans and phenols.

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Green Extraction Techniques for Phytoconstituents from Natural Products

Cited by 3 publications

References 47 publications

Exploring Culture Media Diversity to Produce Fungal Secondary Metabolites and Cyborg Cells

Exploring Culture Media Diversity to Produce Fungal Secondary Metabolites and Cyborg Cells

Seeking Optimal Extraction Method for Augmenting Hibiscus sabdariffa Bioactive Compounds and Antioxidant Activity

The Effect of Green Extraction Technologies on the Chemical Composition of Medicinal Chaga Mushroom Extracts

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