Green Synthesised Silver Nanoparticles Using Anoectochilus elatus Leaf Extract: Characterisation and Evaluation of Antioxidant, Anti-Inflammatory, Antidiabetic, and Antimicrobial Activities

Abstract

The present study investigates the green synthesis of silver nanoparticles was carried out using a leaf extract of Anoectochilus elatus (Ae-AgNPs). The synthesised Ae-AgNPs were characterised using different analytical techniques like UV-visible spectroscopy, X-ray diffraction (XRD), Fourier transform infrared (FTIR), and scanning electron microscopy (SEM) with energy-dispersive X-ray analysis (EDX). Additionally, in vitro activities were investigated, and they possess antioxidant, anti-inflammatory, antidiabetic, and antimicrobial properties. The UV-Vis spectra exhibited characteristic absorption peaks at approximately 480 nm. FTIR identified functional groups of the Ae-AgNPs. The crystalline structure of the Ae-AgNPs was verified via XRD analysis. SEM studies revealed that the nanoparticles exhibited a spherical morphology. The fabrication of Ae-AgNPs was established by the EDX spectrum, which exhibited prominent signals of silver atoms. The Ae-AgNPs show potent antioxidant, anti-inflammatory, and antidiabetic activity compared to standard drugs. In addition, Ae-AgNPs demonstrated the most significant zone of Inhibition. This study affirms the superior biological capability of Ae-AgNPs for target drug delivery and their potential for usage in biomedical research and therapeutics.

Biogenic synthesis, characterization, and in vitro biological investigation of silver oxide nanoparticles (AgONPs) using Rhynchosia capitata

“…Nanoparticles possess unique properties with broad applications in biomedicine, drug delivery, cosmetics, electronics, optics, energy, and bioremediation, attracting global research interest 3 , 4 . Several techniques exist to produce nanoparticles, involving chemical, physical, and biological approaches, each given its own set of advantages and limitations 5 . Among these approaches, the biological synthesis of nanoparticles offers notable advantages, particularly due to its simplicity, environmental friendliness, and elimination of the need for toxic and expensive chemicals to reduce, stabilize, and coat precursor salts 6 , 7 .…”