Currently, there is an active development of environmentally friendly methods of farming. However, the range of products for this type of farming system is limited. Growth stimulation is one of the mechanisms ensuring plant resistance to diseases that reduce crop yields. The aim of the work is to study the effect of laboratory samples of new biological products based on B. subtilis BZR 336 g, B. subtilis BZR 517, P. chlororaphis 245 F strains and organo-mineral fertilizers PRK White Pearl Brown (WPB) and PRK White Pearl Universal” (WPU) on plant growth and development of plants, as well as study of the possibility of their joint use for subsequent inclusion in organic farming systems or integrated plant protection. Growthpromoting ability was assessed in winter wheat and sunflower plants grown in sand in a climatic chamber. As comparison variants there were seed treatment with water (control), chemical (Dividend Star, KS) and biological (Fitosporin-M, F, B. subtilis 26 D) standards. In two plant cultures there was an expected retardant effect of the chemical standard and the growth-promoting effect of the biological standard. Statistically significant data were obtained for such a parameter as the shoot length. On winter wheat, laboratory samples provided the shoot length of 24.1-25.2 mm (an addition to the control of 3.4-8.2%), organic and mineral fertilizers - 23.9-24.5 mm (2.6-5.2%), mixtures with WPU - 23.2-24.4 mm (-0.4-4.7%), mixtures with WPB - 24.1-25.9 mm (3.4-11.2%), a significant increase in root length was not observed in this culture. On winter wheat, it is advisable to use the studied products separately. Sunflower is more responsive to the action of laboratory samples. They provided a shoot length of 13.6-14.6 mm (20.9-27.0%) and a root of 9.2-10.2 mm (4.5-15.9%). Organo-mineral fertilizers provided a shoot length of 14.2-14.5 mm (23.5-26.1%) and the root length of 10.8 mm (22.7%). Mixtures with WPU provided shoot length of 14.7-15.4 mm (27.8-33.9%), mixtures with WPB provided shoot length of 11.9-14.5 mm (3.5-26.1%), and no significant increase in root length was noted. The data obtained indicate the presence in the laboratory samples of fungicidal biological products growth-promoting properties, which vary depending on the culture and additionally used organic and mineral fertilizers. To confirm the results, additional experiments are necessary. Research in this direction will allow the rational use of the studied means of protection and increase plant yields in systems of organic, ecologized and integrated farming, and can help reduce the pesticidal pressure on agrocenoses.Conflict of interest: the authors stated that there was no conflict of interest.