Growing-Related Changes in Arterial Properties of Healthy Children, Adolescents, and Young Adults Nonexposed to Cardiovascular Risk Factors: Analysis of Gender-Related Differences

Curcio, Santiago; García-Espinosa, Victoria; Arana, Maite; Farro, Ignacio; Chiesa, Pedro; Giachetto, Gustavo; Zócalo, Yanina

doi:10.1155/2016/4982676

Cited by 33 publications

(32 citation statements)

References 44 publications

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“…Three examinations were taken from both common carotid arteries and means were calculated to estimate the overall IMT. cIMT was assessed by sex-specific curves for age and increased cIMT was defined as cIMT>90%, which shows atherosclerosis 14 .…”

Section: Carotid Intima-media Thicknessmentioning

confidence: 99%

Carotid intima-media thickness and arterial stiffness as early markers of atherosclerosis in pediatric celiac disease

et al. 2016

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The association between pediatric celiac disease (CD) and atherosclerosis is unknown. Our aim was to investigate whether pediatric CD patients have an increased risk of atherosclerosis. We evaluated the premature atherosclerosis by pulse wave velocity (PWV) and carotid intima-media thickness (cIMT). A total of 37 CD patients (20 girls, mean age 13±3.3 years) and 36 healthy age and sex matched controls were enrolled. Mean duration of CD was 47.1±32.3 months and 40.5% of patients had positive tissue transglutaminase antibody (tTg) IgA. Total cholesterol level was lower in CD (p=0.026) and cIMT was lower in tTg IgA antibody negative CD (p=0.030). cIMT was significantly correlated with tTg IgA antibody positivity (r=0.336; p=0.042). Adherence to strict gluten-free diet is associated with decreased cIMT, suggesting that gluten withdrawal seems to have a beneficial effect on premature atherosclerosis.

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Section: Carotid Intima-media Thicknessmentioning

confidence: 99%

Carotid intima-media thickness and arterial stiffness as early markers of atherosclerosis in pediatric celiac disease

et al. 2016

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“…Healthy subjects (n = 1449; 3-88 years) from the community were considered for enrolment (Table 1) [18][19][20][21][22]. Hypertension, diabetes or dyslipidemia were considered present if the subject reported being in treatment and/or a previous diagnosis of their condition.…”

Section: Methodsmentioning

confidence: 99%

“…[RIs]) of cardiovascular variables in several populations; with special emphasis which considers childhood, adolescence and/or adult life as a continuum [18][19][20][21][22][23].…”

Section: Introductionmentioning

confidence: 99%

Stroke volume and cardiac output non-invasive monitoring based on brachial oscillometry-derived pulse contour analysis: Explanatory variables and reference intervals throughout life (3–88 years)

et al. 2021

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Background: Non-invasive assessment of stroke volume (SV), cardiac output (CO) and cardiac index (CI) has shown to be useful for the evaluation, diagnosis and/or management of different clinical conditions. Through pulse contour analysis (PCA) cuff-based oscillometric devices would enable obtaining ambulatory operator-independent non-invasive hemodynamic monitoring. There are no reference intervals (RIs), when considered as a continuum in childhood, adolescence and adult life, for PCA-derived SV [SV(PCA)], CO [CO(PCA)] and CI [CI(PCA)]. The aim of the study were to analyze the associations of SV(PCA), CO(PCA) and CI(PCA) with demographic, anthropometric, cardiovascular risk factors (CVRFs) and hemodynamic parameters, and to define RIs and percentile curves for SV(PCA), CO(PCA) and CI(PCA), considering the variables that should be considered when expressing them. Methods:In 1449 healthy subjects (3-88 years) SV(PCA), CO(PCA) and CI(PCA) were noninvasively obtained (Mobil-O-Graph; Germany). Analysis: associations between subject characteristics and SV(PCA), CO(PCA) and CI(PCA) levels (correlations; regression models); RIs and percentiles for SV(PCA), CO(PCA) and CI(PCA) (parametric methods; fractional polynomials).Results: Sex, age, and heart rate would be explanatory variables for SV, CO, and CI levels. SV levels were also examined by body height, while body surface area (BSA) contributing to evaluation of CO and CI. CVRFs exposure did not contribute to independently explain the values of the dependent variables. SV, CO and CI levels were partially explained by the oscillometric-derived signal quality. RIs and percentiles were defined. Conclusions:Reference intervals and percentile for SV(PCA), CO(PCA) and CI(PCA), were defined for subjects from 3-88 years of age, results are expressed according to sex, age, heart rate, body height and/or BSA.

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“…Aging is an inevitable and integral factor of childhood; therefore, the results obtained from these studies should be interpreted carefully . Few longitudinal studies have reported on the risk factors of atherosclerotic change in children .…”

mentioning

confidence: 99%

“…[10][11][12][13][14][15] Aging is an inevitable and integral factor of childhood; therefore, the results obtained from these studies should be interpreted carefully. 16 Few longitudinal studies have reported on the risk factors of atherosclerotic change in children. [17][18][19] The aim of the present study was hence to conduct a longitudinal study on the effect of lifestyle on PWV in junior high school students over a period of 3 years, from seventh to ninth grades.…”

mentioning

confidence: 99%

Arterial stiffness in junior high school students: Longitudinal observations

Fujiwara

Nakajima

Inoue

et al. 2018

Pediatrics International

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Background: Early atherosclerotic change is found even in childhood, and there is an urgent need to clarify the factors causing childhood atherosclerosis and take preventive measures. Early detection of the contributing risk factors is crucial to facilitate preventive measures. Pulse wave velocity (PWV) is a widely used technique for the assessment of atherosclerosis in children. Obese students had higher baPWV than non-obese students in both genders across each grade. On logistic regression analysis of ninth grade student data, high baPWV was dependent on systolic blood pressure (SBP), time watching television (TV) and symptoms of depression and anxiety, whereas low baPWV was dependent on time playing video games, light exercise, sleep and indoor play, as well as good friendship and motivation. Conclusion: Systolic blood pressure, time watching TV, and symptoms of depression and anxiety may contribute to arterial stiffness and be related to obesity in junior high school students.

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Growing-Related Changes in Arterial Properties of Healthy Children, Adolescents, and Young Adults Nonexposed to Cardiovascular Risk Factors: Analysis of Gender-Related Differences

Cited by 33 publications

References 44 publications

Carotid intima-media thickness and arterial stiffness as early markers of atherosclerosis in pediatric celiac disease

Carotid intima-media thickness and arterial stiffness as early markers of atherosclerosis in pediatric celiac disease

Stroke volume and cardiac output non-invasive monitoring based on brachial oscillometry-derived pulse contour analysis: Explanatory variables and reference intervals throughout life (3–88 years)

Arterial stiffness in junior high school students: Longitudinal observations

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