2022
DOI: 10.12688/f1000research.122221.2
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Growth kinetics of multiple Acinetobacter baumannii resistotype after meropenem-based antibiotic combination exposure

Abstract: Background: Carbapenems are the treatment of choice for multidrug-resistant (MDR) and extensively drug-resistant (XDR) Acinetobacter baumannii infections, but the emergence of carbapenem-resistant A. baumannii (CRAB) has rendered it ineffective in the vast majority of cases. Combination therapy has grown in popularity over the last decade; this study aims to analyze A.baumannii growth kinetics after exposure to meropenem and ampicillin-sulbactam compared with meropenem and amikacin antibiotic combinations in c… Show more

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