Guanidine Cellulose for Biocompatible Nanoparticles Phase Transfer

Abstract

The introduction of 1, 1, 3, 3‐tetramethyl guanidine groups with degree of substitution of 0.18 into cellulose can tailor the solubility of cellulose in water, which leads to a general and robust development of biopolymer‐based biodegradable and biocompatible material for phase‐transfer of hydrophobic biocompatible nanoparticles to aqueous solution. Fourier transform infrared spectroscopy shows the successful ligand exchange between small molecules and 1, 1, 3, 3‐tetramethyl guanidine functionalized cellulose during the phase transfer. Transmission electron microscope images of the original and transferred nanoparticles confirm the success of the phase transfer without obvious agglomeration occurred. The transferred nanoparticles possessed their own unique properties such as surface plasmon resonance, magnetism, up‐conversion fluorescence.

Self‐Assembly of L‐Arginine on Electrophoretically Deposited Hydroxyapatite Coatings

“…Similarly, previous studies with L‐Arg show that incorporation of L‐Arg is likely to increase the hydrophilicity of surfaces ,. These studies attribute the increase of wettability to the presence of guanido carbonium and carboxyl ions which can form strong hydrogen bonds with H 2 O ,,. Figure b demonstrates AFM images of HA and L‐Arg modified coatings.…”