Guest–host van der Waals interactions decisively affect the molecular transport in mesoporous media

Ukmar, Tina; Maver, Uroš; Planinšek, Odon; Pintar, Albin; Kaučič, Venceslav; Godec, Aljaž; Gaberšček, Miran

doi:10.1039/c1jm13493k

Cited by 20 publications

(12 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this way, we measured the metal ion adsorption contents only using the ICP-AES instrument described above. [23]. The result is in good agreement with previous reports, which confirmed the successful formation of ordered mesophase.…”

Section: Adsorption Of Metal Ions From Solution 1 By Pristine-mcm-41supporting

confidence: 94%

See 1 more Smart Citation

Diffusion mediated selective adsorption of Zn2+ from artificial seawater by MCM-41

Mathew

Parambadath

Kim

et al. 2016

Microporous and Mesoporous Materials

View full text Add to dashboard Cite

Section: Adsorption Of Metal Ions From Solution 1 By Pristine-mcm-41supporting

confidence: 94%

“…MCM-41 was synthesized by using CTAB as the structure directing agent and TEOS as the silica source [23]. The reaction procedure was as follows; CTAB (0.5 g, 1.4 mmol) and ammonia solution (26.7 g, 27%) were taken in distilled water (105 g).…”

Section: Synthesis Of Mcm-41mentioning

confidence: 99%

Diffusion mediated selective adsorption of Zn2+ from artificial seawater by MCM-41

Mathew

Parambadath

Kim

et al. 2016

Microporous and Mesoporous Materials

View full text Add to dashboard Cite

“…The kinetics of drug release is affected by the strength (i.e., the energy) of the specific interaction between the drug molecules and the pore walls. [39,40] If the interaction is strong, the effective diffusion of the drug molecules are slowed. In this case, the release kinetics is at least partially controlled by the aforementioned specific interaction.…”

Section: Release Kinetics In Pbsmentioning

confidence: 99%

Mechanism of drug release from silica-gelatin aerogel—Relationship between matrix structure and release kinetics

Veres

Kéri

Bányai

et al. 2017

Colloids and Surfaces B: Biointerfaces

View full text Add to dashboard Cite

Specific features of a silica-gelatin aerogel (3 wt.% gelatin content) in relation to drug delivery has been studied. It was confirmed that the release of both ibuprofen (IBU) and ketoprofen (KET) is about tenfold faster from loaded silica-gelatin aerogel than from pure silica aerogel, although the two matrices are structurally very similar. The main goal of the study was to understand the mechanistic background of the striking difference between the delivery properties of these closely related porous materials. Hydrated and dispersed silica-gelatin aerogel has been characterized by NMR cryoporometry, diffusiometry and relaxometry. The pore structure of the silica aerogel remains intact when it disintegrates in water. In contrast, dispersed silica-gelatin aerogel develops a strong hydration sphere, which reshapes the pore walls and deforms the pore structure. The drug release kinetics was studied on a few minutes time scale with 1s time resolution. Simultaneous evaluation of all relevant kinetic and structural information confirmed that strong hydration of the silica-gelatin skeleton facilitates the rapid desorption and dissolution of the drugs from the loaded aerogel. Such a driving force is not operative in pure silica aerogels.

show abstract

“…For this purpose, we applied several models to describe the respective release profiles according to 90 91 92 . The authors of the present study have studied different materials and their release performances before 58 93 94 95 96 97 . Unfortunately, as simple as our system may seem (schematically depicted in Fig.…”

Section: Resultsmentioning

confidence: 99%

Novel chitosan/diclofenac coatings on medical grade stainless steel for hip replacement applications

Finšgar

Uzunalić

Stergar

et al. 2016

Sci Rep

Self Cite

View full text Add to dashboard Cite

Corrosion resistance, biocompatibility, improved osteointegration, as well the prevention of inflammation and pain are the most desired characteristics of hip replacement implants. In this study we introduce a novel multi-layered coating on AISI 316LVM stainless steel that shows promise with regard to all mentioned characteristics. The coating is prepared from alternating layers of the biocompatible polysaccharide chitosan and the non-steroid anti-inflammatory drug (NSAID), diclofenac. Electrochemical methods were employed to characterize the corrosion behavior of coated and uncoated samples in physiological solution. It is shown that these coatings improve corrosion resistance. It was also found that these coatings release the incorporated drug in controlled, multi-mechanism manner. Adding additional layers on top of the as-prepared samples, has potential for further tailoring of the release profile and increasing the drug dose. Biocompatibility was proven on human-derived osteoblasts in several experiments. Only viable cells were found on the sample surface after incubation of the samples with the same cell line. This novel coating could prove important for prolongation of the application potential of steel-based hip replacements, which are these days often replaced by more expensive ceramic or other metal alloys.

show abstract

Guest–host van der Waals interactions decisively affect the molecular transport in mesoporous media

Cited by 20 publications

References 39 publications

Diffusion mediated selective adsorption of Zn2+ from artificial seawater by MCM-41

Diffusion mediated selective adsorption of Zn2+ from artificial seawater by MCM-41

Mechanism of drug release from silica-gelatin aerogel—Relationship between matrix structure and release kinetics

Novel chitosan/diclofenac coatings on medical grade stainless steel for hip replacement applications

Contact Info

Product

Resources

About