Guía de la EAU sobre el cáncer de próstata. Parte I: cribado, diagnóstico y tratamiento del cáncer clínicamente localizado

Heidenreich, Axel; Bellmunt, Joaquim; Bolla, M.; Joniau, Steven; Mason, Malcolm David; Матвеев, В. Б.; Mottet, Nicolas; Schmid, Hans‐Peter; Kwast, Theodorus H. van der; Wiegel, Thomas; Zattoni, F.

doi:10.1016/j.acuro.2011.04.004

Cited by 61 publications

(19 citation statements)

References 92 publications

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“…Despite the low specificity of PSA testing and the low sensitivity of SB, these techniques remain the standard of care for PCa diagnosis, mainly because of the high availability and low costs [3–5]. Nevertheless, on the one hand, this strategy misses significant PCa in a high percentage of patients and, on the other hand, detects many insignificant PCa, which leads to overdiagnosis and overtherapy [6].…”

Section: Introductionmentioning

confidence: 99%

Real-Time Elastography of the Prostate

Junker

Zordo

Quentin

et al. 2014

BioMed Research International

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Palpation of organs is one of the oldest clinical examination techniques, for instance, if you think of the palpation of the breast or the digital rectal examination of the prostate, where hard palpable regions are suspicious for cancer. This is the basic principle of real-time elastography, an ultrasound technique, which is able to visualise tissue elasticity. Since prostate cancer features an increased stiffness due to the higher cell and vessel density than the normal surrounding tissue, real-time elastography has been used for several years for prostate cancer detection. This review introduces the different techniques of ultrasound elastography and furthermore summarises its limitations and potentials.

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Section: Introductionmentioning

confidence: 99%

Real-Time Elastography of the Prostate

Junker

Zordo

Quentin

et al. 2014

BioMed Research International

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“…However, a recent report clearly indicates the benefit of DRE in the detection of high risk prostate cancer among men with low PSA [8]. Currently, DRE is essential for the diagnostic procedures associated with prostate cancer [5] despite the fact that prostate cancer diagnostic procedures are due to PSA screening in most cases [9]. DRE, PSA, TRUS and biopsy are the methods that are recommended [5].…”

Section: Discussionmentioning

confidence: 99%

“…Currently, DRE is essential for the diagnostic procedures associated with prostate cancer [5] despite the fact that prostate cancer diagnostic procedures are due to PSA screening in most cases [9]. DRE, PSA, TRUS and biopsy are the methods that are recommended [5]. A bone scan is also an important diagnostic tool, but should only be used for cases with a high risk of bone metastases [5].…”

Section: Discussionmentioning

confidence: 99%

“…DRE, PSA, TRUS and biopsy are the methods that are recommended [5]. A bone scan is also an important diagnostic tool, but should only be used for cases with a high risk of bone metastases [5]. …”

Section: Discussionmentioning

confidence: 99%

“…Despite the huge efforts aimed at prostate cancer research, the prostate-specific antigen (PSA) still remains the main indicator for asymptomatic or mildly symptomatic prostate cancer detection [5]. The aim of the current study was to evaluate how the symptoms leading to prostate cancer diagnosis and the diagnostic procedures used have evolved in Northern Finland over a period of 20 years and what effects these changes have brought with them.…”

Section: Introductionmentioning

confidence: 99%

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Changing trends in symptomatology, diagnostics, stage and survival of prostate cancer in Northern Finland during a period of 20 years

et al. 2013

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BackgroundProstate cancer is the most common cancer among men in many countries. The aim of the present study was to find out how the symptoms leading to a diagnosis, diagnostic procedures and stages of the disease among prostate cancer patients have changed over a period of 20 years.MethodsThis retrospective chart review consisted of 421 prostate cancer patients whose treatment was started in the years 1982, 1987, 1992, 1997 and 2002 at the Oulu University Hospital. Earlier prostatic disorders, specific urological symptoms, diagnostic procedures, the TNM classification and histological grade were recorded.ResultsThe number of symptom-free prostate cancer patients increased over the 20 years, as did the number of men suffering from chronic prostatitis, although the latter increase was not statistically significant. A drop in the number of clinical T4 cases and increase of clinical T1 and clinical T2 cases was recorded but no clear change in the histological distribution occurred. The 5-year prostate cancer-specific survival improved significantly over the 20 years. The urologist was found to be the person who was contacted first most often.ConclusionsOur data indicate that the number of prostate cancer patients has increased hugely over the period from 1982 to 2002 and although the clinical T stage has moved towards earlier stages, the proportion of well differentiated cancers remains low, so that most patients have clinically significant cancer with the need of some form of therapy. Further, prostate cancer-specific survival improved significantly over the period.

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