Guidelines for cardiac pacing and cardiac resynchronization therapy: The Task Force for Cardiac Pacing and Cardiac Resynchronization Therapy of the European Society of Cardiology. Developed in Collaboration with the European Heart Rhythm Association

Vardas, Panos; Auricchio, Angelo; Blanc, Jean‐Jacques; Daubert, Jean‐Claude; Drexler, Helmut; Ector, Hugo; Gasparini, Maurizio; Linde, Cecilia; Morgado, F; Oto, Ali̇; Sutton, Richard; Trusz‐Gluza, Maria; Vahanian, Alec; Caterina, Raffaele De; Dean, Veronica; Dickstein, Kenneth; Funck‐Brentano, Christian; Filippatos, Gerasimos; Hellemans, Irene; Kristensen, Steen Dalby; McGregor, Keith; Sechtem, Udo; Silber, Sigmund; Tendera, Michał; Widimský, Petr; Zamorano, José Luís; Priori, Silvia G.; Blomström‐Lundqvist, Carina; Brignole, Michele; Terradellas, Josep Brugada; Camm, John; Castellano, Perez; Cleland, John G.F.; Farré, Jerónimo; Fromer, Martin; Heuzey, J.-Y. Le; Lip, Gregory Y.H.; Merino, José Luís; Montenero, A. S.; Ritter, Philippe; Schalij, Martin J.; Stellbrink, C.

doi:10.1093/eurheartj/ehm305

Cited by 649 publications

(141 citation statements)

References 365 publications

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“…All patients had drug‐refractory heart failure symptoms, LVEF ≤35% and prolonged QRS duration (≥120 ms) according to recommendations 12, 13. Patients with right ventricular pacing who received an upgrade of the device were excluded from this analysis.…”

Section: Methodsmentioning

confidence: 99%

QRS duration versus morphology and survival after cardiac resynchronization therapy

et al. 2016

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AimsThe prognostic implications of QRS duration and morphology in heart failure patients treated with cardiac resynchronization therapy (CRT) remains debated. The present evaluation investigated the association between QRS duration (<150 vs. ≥150 ms) and QRS morphology (left bundle brand block [LBBB] vs. non‐LBBB) and long‐term prognosis of a large cohort of unselected heart failure patients treated with CRT according to contemporary guidelines.Methods and resultsOf 973 heart failure patients treated with CRT (mean age 66.1 ± 9.8 years, 76% male), 658 patients (68%) showed QRS duration ≥150 ms, and 772 patients (79%) had LBBB configuration. Compared with patients with QRS duration <150 ms, patients with QRS duration ≥150 ms had less frequently ischaemic cardiomyopathy and atrial fibrillation and showed larger left ventricular volumes and lower left ventricular ejection fraction. Compared with patients with non‐LBBB configuration, patients with LBBB morphology were younger, less often males and less often had ischaemic cardiomyopathy and atrial fibrillation. On multivariable analysis, after correcting for relevant clinical and echocardiographic variables, LBBB morphology was significantly associated with better survival [hazard ratio (HR) 0.737; 95% confidence interval (CI) 0.584–0.931; P = 0.010], whereas there was no statistically significant association between QRS duration ≥150 ms and survival (HR 0.889; 95% CI 0.726–1.088; P = 0.252).ConclusionsIn this large population of heart failure patients treated with CRT, QRS morphology was independently associated with long‐term survival. The association between QRS duration and long‐term survival was not statistically significant.

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Section: Methodsmentioning

confidence: 99%

QRS duration versus morphology and survival after cardiac resynchronization therapy

et al. 2016

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“…Syncope is probably the most important symptom in patients with an indication for treatment due to bradycardia. 13 However, the UK is far behind other Western European countries in rates of pacemaker implantation. The average implantation rate on the Continent is over 900/million, and the UK rate is 460/million, with a target of 700/million.…”

Section: Discussionmentioning

confidence: 99%

Initial experience with a rapid access blackouts triage clinic

Petkar¹,

Bell²,

Rice³

et al. 2011

Clinical Medicine

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-Transient loss of consciousness (T-LOC), or blackout, is common in acute medicine. Clinical skills are not done well, with at least 74,000 patients misdiagnosed and mistreated for epilepsy in England alone. The aim of this study was to provide a rapid, structured assessment and an electrocardiogram (ECG) for patients with blackouts, aiming to identify high risk, reduce misdiagnoses, reduce hospital admission rates for low-risk patients, diagnose and treat where appropriate, and also provide onward specialist referral. The majority of patients had syncope, and very few had epilepsy. A high proportion had an abnormal ECG. A specialist-nurse-led rapid access blackouts triage clinic (RABTC) provided rapid effective triage for risk, a comprehensive assessment format, direct treatment for many patients, and otherwise a prompt appropriate onward referral. Rapid assessment through a RABTC reduced re-admissions with blackouts. Widespread use of the web-based blackouts tool could provide the NHS with a performance map. The UK has low rates of pacing compared to Western Europe, which RABTCs might help correct. The RABTC sits between first responders and specialist referral, providing clinical assessment and ECG in all cases, and referral where appropriate.

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“…Lots of studies report improvement in survival rates among patients with third-degree AVB who are using permanent cardiac pacemakers [11][12][13][14][15][16][17]. However, in the first-degree AVB, the indication of pacing is controversial.…”

Section: Indications Of Pacing In Atrioventricular Blockmentioning

confidence: 99%

“…Based on this potentially life-threatening condition, lots of modalities were developed many years ago including drug therapies and device therapy (i.e. pacemaker) to support patients' conditions [10,11]. Drugs, such as anticholinergic agents (i.e.…”

Section: Introductionmentioning

confidence: 99%

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Leadless Cardiac Pacemaker as a Novel Intervention Modality for Atrioventricular Conduction Disturbance in Hypertrophic Cardiomyopathy

Sutanto

2017

J.ATAMIS

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Atrioventricular conduction disturbance is a common complication of cardiovascular diseases, such as hypertrophic cardiomyopathy. Moreover, the most common form of atrioventricular conduction disturbance is atrioventricular block. Until recently, cardiac pacing was considered to be the most reliable long-time management of atrioventricular block. However, cardiac pacemakers have several limitations and complications. When the first generation of leadless pacemakers was invented in the 1980s, it was multi-component. Nowadays, self-contained or single component leadless pacemakers have been developed and have become popular amongst cardiac electrophysiologists. In particular, in 2013, St. Jude Medical developed a novel design for a cardiac pacemaker called the NanostimTM Leadless Pacemaker. In 2015, Medtronic released a smaller leadless pacemaker called the MicraTM Transcatheter Pacing System.1,2 Although NanostimTM and MicraTM represent state of the art technology; a few studies have documented some of their limitations.3-6 More research is needed to confirm and solve these problems

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Guidelines for cardiac pacing and cardiac resynchronization therapy: The Task Force for Cardiac Pacing and Cardiac Resynchronization Therapy of the European Society of Cardiology. Developed in Collaboration with the European Heart Rhythm Association

Cited by 649 publications

References 365 publications

QRS duration versus morphology and survival after cardiac resynchronization therapy

QRS duration versus morphology and survival after cardiac resynchronization therapy

Initial experience with a rapid access blackouts triage clinic

Leadless Cardiac Pacemaker as a Novel Intervention Modality for Atrioventricular Conduction Disturbance in Hypertrophic Cardiomyopathy

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