Guilty by dissociation: Part B: evaluation of Supercritical Fluid Chromatography (SFC-UV) for the analysis of regioisomeric diphenidine-derived Novel Psychoactive Substances (NPS)

A structural spectroscopic study of dissociative anaesthetic methoxphenidine

“…21,22 On the other hand, MXP can be detected using HPLC-MS methods either focused on the analyses of a large amount of samples in biological materials, 23 hair 24 or those focused on the separation of specific regioisomers of the MXP. [25][26][27][28] Similar to arylcyclohexylamines, MXP contains a stereogenic centre in its molecular structure. This fact is disregarded by the manufacturers and, therefore, it is present in drug market as a racemic mixture.…”

“…21,22 On the other hand, MXP can be detected using HPLC-MS methods either focused on the analyses of a large amount of samples in biological materials, 23 hair 24 or those focused on the separation of specific regioisomers of the MXP. 25–28…”