Gum-based cerium oxide nanoparticles for antimicrobial assay

Rahdar, Abbas; Beyzaei, Hamid; Askari, Faezeh; Kyzas, George Z.

doi:10.1007/s00339-020-03507-4

Cited by 33 publications

(15 citation statements)

References 60 publications

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“…The R h values determined for CeO 2 _OC_150 and CeO 2 _OL_150 confirm the presence of clusters observed by TEM images, and of single nanoparticles for CeO 2 _OL_250. Furthermore, taking into account the R h value and the core dimension as determined by TEM, thickness of the coating layer of about 2.5 nm was calculated, in agreement with oleylamine length in its full-length extension (2.0 nm) [ 56 ].…”

Section: Resultsmentioning

confidence: 83%

“…Optical properties are strongly influenced by the use of different capping agents and temperatures: the use of octylamine, in the place of oleylamine, causes strong absorption even in the visible region; this last evidence has been interpreted as a major presence of Ce 3+ with respect to Ce 4+ species [ 53 , 54 , 55 , 56 , 60 ]. This evidence can also be the cause of a peak splitting in the fluorescence spectrum.…”

Section: Discussionmentioning

confidence: 99%

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Towards the Development of Antioxidant Cerium Oxide Nanoparticles for Biomedical Applications: Controlling the Properties by Tuning Synthesis Conditions

et al. 2021

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In this work CeO2 nanoparticles (CeO2-NPs) were synthesized through the thermal decomposition of Ce(NO3)3·6H2O, using as capping agents either octylamine or oleylamine, to evaluate the effect of alkyl chain length, an issue at 150 °C, in the case of octylamine and at 150 and 250 °C, in the case of oleylamine, to evaluate the effect of the temperature on NPs properties. All the nanoparticles were extensively characterized by a multidisciplinary approach, such as wide-angle X-ray diffraction, transmission electron microscopy, dynamic light scattering, UV-Vis, fluorescence, Raman and FTIR spectroscopies. The analysis of the experimental data shows that the capping agent nature and the synthesis temperature affect nanoparticle properties including size, morphology, aggregation and Ce3+/Ce4+ ratio. Such issues have not been discussed yet, at the best of our knowledge, in the literature. Notably, CeO2-NPs synthesized in the presence of oleylamine at 250 °C showed no tendency to aggregation and we made them water-soluble through a further coating with sodium oleate. The obtained nanoparticles show a less tendency to clustering forming stable aggregates (ranging between 14 and 22 nm) of few NPs. These were tested for biocompatibility and ROS inhibiting activity, demonstrating a remarkable antioxidant activity, against oxidative stress.

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Section: Resultsmentioning

confidence: 83%

Section: Discussionmentioning

confidence: 99%

Towards the Development of Antioxidant Cerium Oxide Nanoparticles for Biomedical Applications: Controlling the Properties by Tuning Synthesis Conditions

et al. 2021

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“…With this in mind, as a continuous effort related to the synthesis of nanomaterials and investigation of their potential in biological applications [ 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 ], we currently review here different nanomaterials applied to diagnosis and treatment of inflammatory arthritis.…”

Section: Introductionmentioning

confidence: 99%

Nanomaterials for the Diagnosis and Treatment of Inflammatory Arthritis

Hosseinikhah

Barani

Rahdar

et al. 2021

IJMS

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Nanomaterials have received increasing attention due to their unique chemical and physical properties for the treatment of rheumatoid arthritis (RA), the most common complex multifactorial joint-associated autoimmune inflammatory disorder. RA is characterized by an inflammation of the synovium with increased production of proinflammatory cytokines (IL-1, IL-6, IL-8, and IL-10) and by the destruction of the articular cartilage and bone, and it is associated with the development of cardiovascular disorders such as heart attack and stroke. While a number of imaging tools allow for the monitoring and diagnosis of inflammatory arthritis, and despite ongoing work to enhance their sensitivity and precision, the proper assessment of RA remains difficult particularly in the early stages of the disease. Our goal here is to describe the benefits of applying various nanomaterials as next-generation RA imaging and detection tools using contrast agents and nanosensors and as improved drug delivery systems for the effective treatment of the disease.

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“…Nanotechnology-based approaches such as gold NPs, silver NPs, magnetic NPs, and quantum dots (QDs) reveal selective target-binding characteristics [42][43][44][45][46][47][48][49][50][51][52][53][54][55][56][57]. These characteristics make them ideal candidates for the diagnosis and biosensing of E. coli infections [58][59][60][61][62][63].…”

Section: Introductionmentioning

confidence: 99%

Nanomaterials in the Management of Gram-Negative Bacterial Infections

et al. 2021

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The exploration of multiplexed bacterial virulence factors is a major problem in the early stages of Escherichia coli infection therapy. Traditional methods for detecting Escherichia coli (E. coli), such as serological experiments, immunoassays, polymerase chain reaction, and isothermal microcalorimetry have some drawbacks. As a result, detecting E. coli in a timely, cost-effective, and sensitive manner is critical for various areas of human safety and health. Intelligent devices based on nanotechnology are paving the way for fast and early detection of E. coli at the point of care. Due to their specific optical, magnetic, and electrical capabilities, nanostructures can play an important role in bacterial sensors. Another one of the applications involved use of nanomaterials in fighting microbial infections, including E. coli mediated infections. Various types of nanomaterials, either used directly as an antibacterial agent such as metallic nanoparticles (NPs) (silver, gold, zinc, etc.), or as a nanocarrier to deliver and target the antibiotic to the E. coli and its infected area. Among different types, polymeric NPs, lipidic nanocarriers, metallic nanocarriers, nanomicelles, nanoemulsion/ nanosuspension, dendrimers, graphene, etc. proved to be effective vehicles to deliver the drug in a controlled fashion at the targeted site with lower off-site drug leakage and side effects.

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Gum-based cerium oxide nanoparticles for antimicrobial assay

Cited by 33 publications

References 60 publications

Towards the Development of Antioxidant Cerium Oxide Nanoparticles for Biomedical Applications: Controlling the Properties by Tuning Synthesis Conditions

Towards the Development of Antioxidant Cerium Oxide Nanoparticles for Biomedical Applications: Controlling the Properties by Tuning Synthesis Conditions

Nanomaterials for the Diagnosis and Treatment of Inflammatory Arthritis

Nanomaterials in the Management of Gram-Negative Bacterial Infections

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