Haematological Profile of Chronic Kidney Disease in a Mixed-Ancestry South African Population

Hematological Indices in Chronic Kidney Disease Patients and The Effect of Hemodialysis on These Indices

“…There are 28 males in 27 females in the control group with a mean age of 40.09 years compared with 28 males and 28 females with a mean age of 57.22 years in the NDD-CKD group and 26 males and 29 females with a mean age of 53.16 in the DD-CKD group. A comparison between the two studied groups (2,3) according to risk factors is demonstrated in Table (2). 40% of the NDD-CKD group are diabetic (n 22) and 81.8% (n 45) are hypertensive, and in the DD-CKD group 40% (n 22) are diabetic and 69.1% (n 38) are hypertensive.…”

“…There are also great changes in the hematological parameters in those patients as Hb%, RBC count, HCT, MCHC, RDW, MCV, or MCH. Total and differential white blood cell (WBC) counts are two other commonly impaired blood parameters in CKD that have yet to be completely characterized concerning CKD (3) . Platelet disorders have been discovered to be an important method for grading severity in CKD patients.…”

Hematological Abnormalities and Comorbidities Are Associated With the Severity of Kidney Disease: A Hospital-Based Cross-Sectional Study in Bangladesh

“…13 The primary cause of anemia among CKD patients is the failure to produce sufficient erythropoietin by kidneys. 14 Moreover, this condition decreases the quality of life and increases the risk of developing other related health problems. 15 Non-treated anemia can result in hemodynamic and tissue hypoxia changes, all of which accelerate renal function decline.…”

“…24 The high ratio of neutrophil and lymphocyte concentrations indicates the inflammatory state in CKD. 14 This ratio is a prognostic indicator of mortality risk in other diseases, for example, myocardial infarction and heart failure. 14 Increased morbidity and mortality from cardiovascular complications may occur in CKD patients due to increased anemia.…”

“…14 This ratio is a prognostic indicator of mortality risk in other diseases, for example, myocardial infarction and heart failure. 14 Increased morbidity and mortality from cardiovascular complications may occur in CKD patients due to increased anemia. 25 The progression of renal disease and the development of cardiorenal anemia syndrome might occur in CKD patients.…”