Haemophilic arthropathy of the elbow

Utukuri, M. M.; Goddard, N J

doi:10.1111/j.1365-2516.2005.01146.x

Cited by 24 publications

(20 citation statements)

References 24 publications

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“…A complication of TEA that our patient population did not encounter is septic loosening or component failure [15]. Furthermore, concurrent HIV infection did not appear to lead to worse outcomes because of prosthesis infection among most of our patients, which is a notion that is supported in the literature [16–18].…”

Section: Discussionmentioning

confidence: 52%

Outcomes in total elbow arthroplasty in patients with haemophilia at the University of California, San Francisco: a retrospective review

Brooks¹,

Tobase²,

Karp³

et al. 2010

Haemophilia

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Severe haemophilic arthropathy of the elbow is a significant cause of morbidity among adults with haemophilia. However, previous reports of total elbow arthroplasty (TEA) in the haemophilic population have been based on small numbers of patients with relatively short-term follow-up. The records of seven total elbow arthroplasties in six adult men with haemophilia at the University of California, San Francisco who underwent TEA over a period of 25 years were retrospectively reviewed. Type of haemophilia, age at time of TEA, HIV infection status, pre- and postoperative range-of-motion (ROM) scores, complications (including infections), need for subsequent surgical revision and functional outcomes were recorded. Four patients had severe factor VIII deficiency and two patients had severe factor IX deficiency. None of the patients had an inhibitor. The mean age at the time of surgery was 34 years (range, 22-46 years) and the mean follow-up period was 118 months (range, 37-176 months). One of the six patients had TEA in both elbows. Five of the six patients were infected with HIV. There were no immediate perioperative complications. At a mean of 19.2 months postoperatively, ROM had improved in five of seven TEAs: mean flexion had increased from 110.7° (SD = 15.0) to 120.1° (SD = 14.5), whereas mean preoperative extension increased from -44.3° (SD = 21.5) to -36.9° (SD = 27.0). One patient required a revision at 30 months because of ulnar component loosening. This same patient sustained a staph epidermidis infection and ultimate removal of the prosthesis 15 years postoperatively. At a mean of 118 months postoperatively, five of six patients continued to report reduced pain and preserved functionality, with ability to perform normal daily activities. TEA resulted in favourable results in six of seven procedures. Our findings support the viability of TEA for individuals with severe haemophilic arthropathy of the elbow, especially to reduce pain and preserve or restore functionality.

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Section: Discussionmentioning

confidence: 52%

Outcomes in total elbow arthroplasty in patients with haemophilia at the University of California, San Francisco: a retrospective review

Brooks¹,

Tobase²,

Karp³

et al. 2010

Haemophilia

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“…Le coude est la seconde articulation touchée par ordre de fréquence dans cette pathologie avec des plaintes intéressant seulement 7 % des patients contre 45 % pour la cheville. En cas d'atteinte du coude, d'autres articulations sont symptomatiques dans 25 % des cas, le genou arrivant en tête [9]. Les constatations radiologiques associent à des degrés variables : déminéralisation osseuse, hypertrophie épiphysaire, pincement articulaire, irrégularité de l'os sous-chondral, géodes sous-chondrales, érosions osseuses, perte de congruence des surfaces articulaires et déformation de l'articulation.…”

Section: Arthropathies Hémophiliquesunclassified

Les arthropathies inflammatoires du coude

Gaudin

2012

Revue du Rhumatisme Monographies

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“…One of the authors carried out clinical and radiological assessment of a group of 26 patients attending the Haemophilia Unit at the Royal Free Hospital, London, with severe haemophilic arthropathy of the elbow [33]. The majority had a functional range of motion of their elbows enabling them to perform normal activities of daily living (ADLs).…”

Section: Elbowmentioning

confidence: 99%

An outline of the current orthopaedic management of haemophilic disease of the upper limb

et al. 2007

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There remains a relative paucity in the literature regarding upper limb manifestations of haemophilic arthropathy. Haemophilia has a wide range of clinical manifestations, often presenting with orthopaedic complications. These arise from multiple haemarthroses which exact a cumulative toll on the fabric of the joints. Although the lower limbs are predominantly affected due to their load-bearing nature, upper limb disease is common. This arises from the mechanical demands on the upper limb as the elbow and shoulder become partially weight bearing on use of walking aids such as elbow crutches.

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Haemophilic arthropathy of the elbow

Cited by 24 publications

References 24 publications

Outcomes in total elbow arthroplasty in patients with haemophilia at the University of California, San Francisco: a retrospective review

Outcomes in total elbow arthroplasty in patients with haemophilia at the University of California, San Francisco: a retrospective review

Les arthropathies inflammatoires du coude

An outline of the current orthopaedic management of haemophilic disease of the upper limb

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