Halogen‐Containing Pyridines. Part 8. Synthesis of 3,5‐Dichloropyridines Containing Pyrazole and Pyrazoline Residues in Position 2.

Кобраков, К. И.; Rybina, I. I.; Келарев, В. И.; Korolev, V. K.

doi:10.1002/chin.200415127

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In Vitro Antimicrobial Activity Test1

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2012

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“…Parameters of MIC (minimal inhibitory concentration) [12] in the antibacterial test are presented in the Table 7. It can be concluded from Table 7 that the three complexes have an inhibiting effect on escherichia coli, staphylococcus aureus and staphylococcus epidermidis at low concentration, but remain inactive towards streptococcus pneumoniae and klebsiella pneumoniae.…”

Section: In Vitro Antimicrobial Activity Testmentioning

confidence: 99%

The Synthesis, Characterization and Application of Ciprofloxacin Complexes and Its Coordination with Copper, Manganese and Zirconium Ions

Tan¹,

Tan²,

Zhao³

et al. 2012

JCPT

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In our work, ciprofloxacin was extracted from the raw material ciprofloxacin hydrochloride and coordinated with the metal ions of copper, manganese and zirconium. The procedures include the comparison of the autoclave method with the solvothermal method, synthesizing the corresponding complexes and conducting antibacterial test on nearly 20 kinds of bacteria. It is shown that under the condition of PH1 and 110℃ - 116℃, the autoclave method and solvothermal method can be utilized to obtain the ciprofloxacin complexes with Cu2+, Mn2+ and Zr2+ as the metal ligands after reacting for 8 hours. The raw material, ligands and monocrystals were characterized by IR, DSC, UV and fluorescence spectrum. Meanwhile a great number of antibacterial tests were carried out, revealing favorable bacteriocidal properties of the resulting complexes

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Section: In Vitro Antimicrobial Activity Testmentioning

confidence: 99%