Hand-Assisted Retroperitoneoscopic Donor Nephrectomy Compared to Anterior Approach Open Donor Nephrectomy: Improved Long-Term Physical Component Score in Health-Related Quality of Life in Living Kidney Donors

Wahba, Roger; Vitinius, Frank; Walczuch, Bianca; Dieplinger, Georg; Buchner, Denise; Datta, Rabi R.; Lürssen, Nadine; Schlößer, Hans; Thomas, Michael; Müller, Roman Ulrich; Kann, Martin; Hellmich, Martin; Kurschat, Christine; Stippel, Dirk L.

doi:10.1016/j.transproceed.2020.08.026

Cited by 3 publications

(1 citation statement)

References 23 publications

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“…Subscale scores are further transformed to a 0-100 scale, with 0 representing the worst well-being and 100 representing the greatest well-being. The SF-36 is well established and validated to measure postoperative recovery after various surgical procedures [13,14] The manuscript was submitted to the local ethics committee which stated that we are exempt from applying for ethical approval, as under German law no separate ethics application and statement of ethical approval by the local ethics committee are required for performing purely retrospective clinical studies. Electronic and paper data of the University Hospital of Cologne were retrospectively collected and analyzed.…”

Section: Methodsmentioning

confidence: 99%

Introduction of laparoscopic nephrectomy for autosomal dominant polycystic kidney disease as the standard procedure

Thomas

Datta

Wahba

et al. 2022

Preprint

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Purpose: Autosomal dominant polycystic kidney disease (ADPKD) is a common hereditary disorder and accounts for 5-10% of all cases of kidney failure. 50% of ADPKD patients reach kidney failure by the age of 58 years requiring dialysis or transplantation. Nephrectomy is performed in up to 20% of patients due to compressive symptoms, renal-related complications or in preparation for kidney transplantation. However, due to the large kidney size in ADPKD nephrectomy can come with a considerable burden. Here we evaluate our institution’s experience of laparoscopic nephrectomy (LN) as an alternative to standard-procedure nephrectomy for ADPKD patients.Materials and Methods: We report the results of the first 12 consecutive laparoscopic cystnephrectomies from 08/2020 to 08/2021 in our institution. Intra- and postoperative parameters were collected and analyzed. Health related quality of life (HRQoL) was assessed using the SF36 questionnaire.Results: Median age of patients was 60 years (±8,1a). Mean preoperative kidney volume measured by volumetric analyzes in abdominal CT scan was 3795ml (range 1255-8253ml). Mean operative time was 158min (range 85-227min). Mean postoperative stay was 11 days (range 6-35 days). Only one postoperative complication Clavien-Dindo ³3 occurred (8,3%). SF36 HRQol questionnaire revealed excellent postoperative quality of life after LN.Conclusion: Laparoscopic nephrectomy in ADPKD patients is a safe and effective operative procedure independent of kidney size with excellent postoperative outcomes and benefits of minimally invasive surgery.

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Section: Methodsmentioning

confidence: 99%

Introduction of laparoscopic nephrectomy for autosomal dominant polycystic kidney disease as the standard procedure

Thomas

Datta

Wahba

et al. 2022

Preprint

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Introduction of laparoscopic nephrectomy for autosomal dominant polycystic kidney disease as the standard procedure

Thomas

Datta

Wahba

et al. 2023

Langenbecks Arch Surg

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Purpose Autosomal dominant polycystic kidney disease (ADPKD) is a common hereditary disorder and accounts for 5–10% of all cases of kidney failure. 50% of ADPKD patients reach kidney failure by the age of 58 years requiring dialysis or transplantation. Nephrectomy is performed in up to 20% of patients due to compressive symptoms, renal-related complications or in preparation for kidney transplantation. However, due to the large kidney size in ADPKD, nephrectomy can come with a considerable burden. Here we evaluate our institution’s experience of laparoscopic nephrectomy (LN) as an alternative to open nephrectomy (ON) for ADPKD patients. Materials and methods We report the results of the first 12 consecutive LN for ADPKD from August 2020 to August 2021 in our institution. These results were compared with the 12 most recent performed ON for ADPKD at the same institution (09/2017 to 07/2020). Intra- and postoperative parameters were collected and analyzed. Health related quality of life (HRQoL) was assessed using the SF36 questionnaire. Results Age, sex, and median preoperative kidney volumes were not significantly different between the two analyzed groups. Intraoperative estimated blood loss was significantly less in the laparoscopic group (33 ml (0–200 ml)) in comparison to the open group (186 ml (0–800 ml)) and postoperative need for blood transfusion was significantly reduced in the laparoscopic group (p = 0.0462). Operative time was significantly longer if LN was performed (158 min (85–227 min)) compared to the open procedure (107 min (56–174 min)) (p = 0.0079). In both groups one postoperative complication Clavien Dindo ≥ 3 occurred with the need of revision surgery. SF36 HRQol questionnaire revealed excellent postoperative quality of life after LN. Conclusion LN in ADPKD patients is a safe and effective operative procedure independent of kidney size with excellent postoperative outcomes and benefits of minimally invasive surgery. Compared with the open procedure patients profit from significantly less need for transfusion with comparable postoperative complication rates. However significant longer operation times need to be taken in account.

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Living Kidney Donation: A Narrative Review of Mid- and Long-term Psychosocial Outcomes

Massey,

Rule,

Matas

2024

Transplantation

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Living kidney donors make a significant contribution to alleviating the organ shortage. The aim of this article is to provide an overview of mid- and long-term (≥12 mo) living donor psychosocial outcomes and highlight areas that have been understudied and should be immediately addressed in both research and clinical practice. We conducted a narrative review by searching 3 databases. A total of 206 articles were included. Living donors can be divided into those who donate to an emotionally or genetically related person, the so-called directed donors, or to an emotionally or genetically unrelated recipient, the so-called nondirected donors. The most commonly investigated (bio)psychosocial outcome after living donation was health-related quality of life. Other generic (bio)psychological outcomes include specific aspects of mental health such as depression, and fatigue and pain. Social outcomes include financial and employment burdens and problems with insurance. Donation-specific psychosocial outcomes include regret, satisfaction, feelings of abandonment and unmet needs, and benefits of living kidney donation. The experience of living donation is complex and multifaceted, reflected in the co-occurrence of both benefits and burden after donation. Noticeably, no interventions have been developed to improve mid- or long-term psychosocial outcomes among living donors. We highlight areas for methodological improvement and identified 3 areas requiring immediate attention from the transplant community in both research and clinical care: (1) recognizing and providing care for the minority of donors who have poorer long-term psychosocial outcomes after donation, (2) minimizing donation-related financial burden, and (3) studying interventions to minimize long-term psychosocial problems.

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Hand-Assisted Retroperitoneoscopic Donor Nephrectomy Compared to Anterior Approach Open Donor Nephrectomy: Improved Long-Term Physical Component Score in Health-Related Quality of Life in Living Kidney Donors

Cited by 3 publications

References 23 publications

Introduction of laparoscopic nephrectomy for autosomal dominant polycystic kidney disease as the standard procedure

Introduction of laparoscopic nephrectomy for autosomal dominant polycystic kidney disease as the standard procedure

Introduction of laparoscopic nephrectomy for autosomal dominant polycystic kidney disease as the standard procedure

Living Kidney Donation: A Narrative Review of Mid- and Long-term Psychosocial Outcomes

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