Hand grip strength in predicting the risk of osteoporosis in Asian adults

Lin, Yen-Huai; Chen, Hsi‐Chung; Hsu, Nan‐Yung; Chou, Pesus; Teng, Michael Mu Huo

doi:10.1007/s00774-020-01150-w

Cited by 19 publications

(16 citation statements)

References 17 publications

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“…Since hand grip strength is easy and cost-effective to measure, it is suitable to be used as an easy assessment method for identifying individuals at a high risk of osteoporosis. The cutoff strength for evaluating osteoporosis in adults is age and sex specific ( 31 ). The results in this study were consistent with the previous studies.…”

Section: Discussionmentioning

confidence: 99%

Osteoporosis and Related Health Status Among the Elderly Urban Residents in Elderly-Care Inns in Beijing, a Multicenter DXA Survey

Lin

Guo²,

Lian³

et al. 2022

Front. Endocrinol.

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BackgroundIdentification of the high risk population for osteoporosis and timely prevention are the best strategies at present. Detailed epidemiological investigation in a well-defined population is necessary to explore the population-based characteristics and risk factors of osteoporosis, thus to facilitate better prevention programs.MethodIn this prospective cross-sectional study, 1423 questionnaires were given out to the urban residents (female ≥ 40 years of age, male ≥50 years) who lived in the 27 Elderly-Care Inns interspersed among the seven central urban areas of Beijing. All participants were voluntary and underwent routine physical examination and spine and hip BMD measurements using the DXA instrument. The study protocols were approved by the Medical Ethics Committee of Dongzhimen Hospital, Beijing University of Chinese Medicine (JDZX2015079).ResultsAltogether 1407 participants fulfilled the survey. Among 359 men, the prevalence of osteoporosis, osteopenia, and normal BMD were 18.1%, 56.6%, and 25.3%, respectively; among 1048 women, the corresponding figures were 40.3%, 42.8%, and 16.9%, respectively. After adjustment of age and BMI, both hands grip strength, height loss over 3 cm, serum levels of β-CTx, PINP, and OST were the independent risk factors for osteoporosis in both men and women; besides, familial Alzheimer’s disease history in men; and history of steatohepatitis and fracture, serum levels of PTH and ALT, age of menarche, age of menopause, and duration of menstruation in women were also risk factors of osteoporosis. In both genders, the cost-effective method, which adopted both hands grip strength, height loss over 3 cm, and medical history, indicated a good predictive ability to evaluate the risk of osteoporosis (in men AUC=0.730, 95%CI=0.642~0.817; in women AUC=0.769, 95%CI=0.724~0.813).ConclusionsIn the population of elderly Beijing urban residents in Elderly-Care Inns, the prevalence of osteoporosis in women is higher than that in men and increases with aging more rapidly; the prevalence of osteopenia in men is higher than in women. The cost-effective method, including both hands grip strength, height loss over 3 cm, and familial Alzheimer’s disease history in men; fracture and steatohepatitis history as well as menstrual history in women is recommended in identifying the high-risk subjects for osteoporosis.

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Section: Discussionmentioning

confidence: 99%

Osteoporosis and Related Health Status Among the Elderly Urban Residents in Elderly-Care Inns in Beijing, a Multicenter DXA Survey

Lin

Guo²,

Lian³

et al. 2022

Front. Endocrinol.

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“…The present study is part of the Cheng Hsin Osteoporosis and Sarcopenia (CHOS) study, which is a cross-sectional hospital-based study that has been ongoing since January 2019. The study design has been detailed elsewhere [ 13 , 14 ]. Post-menopausal Chinese women who had undergone dual-energy X-ray absorptiometry (DXA) examination were recruited, and only those who were willing and with a body mass index of 15–37 kg/m 2 were included in this study.…”

Section: Methodsmentioning

confidence: 99%

“…Hand grip strength (kg) of the dominant hand was measured using a digital dynamometer (EH101; Camry, Guangdong Province, China). The Camry dynamometer was validated with the Jamar dynamometer (Jamar, Jackson, MI, USA) [ 13 , 14 ]. Usual gait speed was measured on a 4-m course using a sensor timer.…”

Section: Methodsmentioning

confidence: 99%

The Impact of the “Osteo” Component of Osteosarcopenia on Fragility Fractures in Post-Menopausal Women

Lin

Shih

Teng

2021

IJMS

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Osteosarcopenia, the coexistence of bone and muscle loss, is common in older adults, but its definition lacks international consensus. This cross-sectional study (n = 1199 post-menopausal women) aimed to determine the association between osteosarcopenia and fragility fractures and to investigate the impact of the definition of the “osteo” component. Bone mineral density and bone microarchitecture were measured by dual-energy X-ray absorptiometry and the trabecular bone score (TBS), respectively. The “osteo” component of osteosarcopenia was classified as osteoporosis (T-score ≤ −2.5 SD), osteopenia/osteoporosis (T-score < −1 SD), and high-fracture-risk osteopenia (−2.5 SD < T-score < −1 SD)/osteoporosis (T-score ≤ −2.5 SD). The Fracture Risk Assessment Tool was used to identify high-fracture-risk osteopenia. Altogether, 30.3%, 32.2%, 14.4%, and 23.1% of participants had osteosarcopenia, osteoporosis alone, sarcopenia alone, and neither condition, respectively. The odds ratios between osteosarcopenia and fragility fractures were 3.70 (95% CI: 1.94–7.04) for osteosarcopenia, 2.48 (95% CI: 1.30–4.71) for osteoporosis alone, and 1.87 (95% CI: 0.84–4.14) for sarcopenia alone. Women with osteosarcopenia also had lower TBS, indicating worse bone microarchitecture. In conclusion, women with osteosarcopenia were more likely to have previously sustained a fracture compared to those without osteosarcopenia, with sarcopenia alone, and with osteoporosis alone. The relationship between osteosarcopenia and fracture risk may be best identified when considering high-fracture-risk osteopenia and osteoporosis.

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“…Additionally, the Camry® dynamometer weighs 1 lbs, while the Jamar® dynamometer weighs 4 lbs. The Camry® dynamometer was validated using the Jamar® dynamometer, and a strong correlation was found [15].…”

Section: Women Menmentioning

confidence: 99%

“…Hand grip strength is another major component in frailty assessment; it is a useful indicator of the current health status. For example, hand grip strength is related to lower bone mineral density or osteoporosis [14,15], malnutrition [16], cognitive impairment [17], multimorbidity [18], depression [19], frailty [4], and long sleep duration [20]. Thus, owing to the high clinical relevance, availability, and accessibility of measuring hand grip strength, it is intuitive to consider the use of hand grip strength as a proxy for the detection of slow walking speed [21][22][23][24][25].…”

Section: Introductionmentioning

confidence: 99%

Using hand grip strength to detect slow walking speed in older adults: the Yilan study

et al. 2021

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Background Walking speed is an important health indicator in older adults, although its measurement can be challenging because of the functional decline due to aging and limited environment. The aim of this study was to examine whether hand grip strength can be a useful proxy for detecting slow walking speed in this population. Methods A cross-sectional study was conducted using the cohort from the Yilan Study in Taiwan. Community-dwelling older adults aged 65 years and older were included. Slow walking speed was defined as a 6-meter walking speed < 1.0 m/s, according to the 2019 Asian Working Group for Sarcopenia diagnostic criteria. Stepwise multiple linear regression was used to determine the most significant variables associated with walking speed. Receiver operating characteristic analysis was used to determine the optimal cutoff values for hand grip strength in detecting slow walking speed. Results A total of 301 participants with an average age of 73.9 ± 6.8 years were included; 55.1 % participants were women. In stepwise multiple linear regression analysis that included various variables, hand grip strength was found to be the most explainable factor associated with walking speed among all participants and among participants of each sex. The optimal cutoff values for hand grip strength in the detection of slow walking speed were 19.73 kg for all participants (sensitivity: 55 %, specificity: 83 %, area under the curve: 0.74, accuracy: 66.9 %), 35.10 kg for men (sensitivity: 92 %, specificity: 42 %, area under the curve: 0.70, accuracy: 66.4 %), and 17.93 kg for women (sensitivity: 62 %, specificity: 80 %, area under the curve: 0.76, accuracy: 67.9 %). Conclusions Hand grip strength was found to be a useful proxy for the identification of slow walking speed in older adults.

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Hand grip strength in predicting the risk of osteoporosis in Asian adults

Cited by 19 publications

References 17 publications

Osteoporosis and Related Health Status Among the Elderly Urban Residents in Elderly-Care Inns in Beijing, a Multicenter DXA Survey

Osteoporosis and Related Health Status Among the Elderly Urban Residents in Elderly-Care Inns in Beijing, a Multicenter DXA Survey

The Impact of the “Osteo” Component of Osteosarcopenia on Fragility Fractures in Post-Menopausal Women

Using hand grip strength to detect slow walking speed in older adults: the Yilan study

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