Hand-held based near-infrared optical imaging devices: A review

Erickson, Sarah J.; Godavarty, Anuradha

doi:10.1016/j.medengphy.2008.10.004

Cited by 75 publications

(54 citation statements)

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“…[18][19][20][21] Our research group together with two instrumentation companies, developed two newly developed NIR imaging devices. 20,21 Their most notable features are not only high sensitivity and high speed but also portability and wide area monitoring.…”

Section: Development Of New Nir Imaging Instrumentsmentioning

confidence: 99%

Recent Progress of Near-Infrared (NIR) Imaging —Development of Novel Instruments and Their Applicability for Practical Situations—

et al. 2014

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The purpose of this review article is to outline the recent progress in near-infrared (NIR) imaging technology with particular emphasis on new instrumentation. Superior features of NIR imaging such as suitability for nondestructive and in-situ analysis, transmission ability, availability of optical fibers, high-speed monitoring and stability are very attractive not only for laboratory-based studies but also for diverse practical applications. In this review, introduction to chemical imaging is described, and then, a comparison among NIR, infrared (IR) and Raman imaging are made. Furthermore, the features of new NIR imaging instruments developed by our research group in collaboration with Yokogawa Electric Corporation and Sumitomo Electric Industries, Ltd. are discussed. Finally, some examples of applications of NIR imaging are introduced. Particularly, the performance and usefulness of the newly-developed imaging devices are demonstrated through their applications to pharmaceutical tablets and polymers.

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Section: Development Of New Nir Imaging Instrumentsmentioning

confidence: 99%

Recent Progress of Near-Infrared (NIR) Imaging —Development of Novel Instruments and Their Applicability for Practical Situations—

et al. 2014

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“…The current technologies' drawbacks make the detection inconvenient and restrain the general examinations basically. 4 With this in mind, it is of great significance to develop a portable, noninvasive, low-cost, and popularized detection method for this disease.…”

Section: Introductionmentioning

confidence: 99%

Tissue phantom-based breast cancer detection using continuous near-infrared sensor

et al. 2016

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Women's health is seriously threatened by breast cancer. Taking advantage of efficient diagnostic instruments to identify the disease is very meaningful in prolonging life. As a cheap noninvasive radiation-free technology, Near-infrared Spectroscopy is suitable for general breast cancer examination. A discrimination method of breast cancer is presented using the deference between absorption coefficients and applied to construct a blood oxygen detection device based on Modified Lambert-Beer theory. Combined with multi-wavelength multi-path near-infrared sensing technology, the proposed method can quantitatively distinguish the normal breast from the abnormal one by measuring the absorption coefficients of breast tissue and the blood oxygen saturation. An objective judgment about the breast tumor is made according to its high absorption of near-infrared light. The phantom experiment is implemented to show the presented method is able to recognize the absorption differences between phantoms and demonstrates its feasibility in the breast tumor detection.

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“…Currently, research involving DOI has seen an increase in the clinical translation of this technology using either bulky bench top or hand-held based optical imagers (examples shown in figure 2.4) [Erickson, et al 2008, Chance, et al 2005Chen, et al 2004;Sao, et a. 2003;Tromberg, et al 2005;Xu, et al 2007;Zhu, et al 1999] for various applications.…”

Section: Clinical Translation Of Optical Imagingmentioning

confidence: 99%

“…The optical data is then coregistered with the ultrasound to combine the functional (from the optical data) with the 14 structural information (from the ultrasound data) and locate a tumor in the tissue [Zhu, et al 2010]. Other groups have developed FD and CW NIR spectroscopic imagers that are capable of collecting both the FD and CW simultaneously allowing for more information about the tissue than just FD or CW alone [Cerussi, et al, 2006;Cerussi, et al, 2007;Erickson, et al 2008], allowing for less post processing to acquire the tissue information.While yet other research groups have also included fluorophores in the tissue or phantoms to enhance the contrast of the image [Erickson, et al 2008].Although various researchers have developed hand-held probe based imagers with multiple sources and detectors, the probe heads were smaller and the studies were more focused on 2D spectroscopic imaging. Other researchers have yet to successfully combine optical imaging with 3D tomography capabilities in a hand held based system.…”

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Performance Enhancement In Accuracy and Imaging Time of a Hand-Held Probe-Based Optical Imager

Martínez¹

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The Optical Imaging Laboratory has developed a hand-held optical imaging system that is capable of 3D tomographic imaging. However, the imaging system is limited by longer imaging times, and inaccuracy in the positional tracking of the handheld probe. Hence, the objective is to improve the performance of the imaging system by Table 3.3 Positions collected in the 2D tracking study for the second generation probe heads. Both probe heads were moved in the same positions on separate phantoms where (0,0) is the bottom right position of the phantom. Therefore each of these positions was repeated 5 times per probe head. ……………………………………………………………………………………....58 Table 4.1 Error comparison of the tracking devices in two dimensional tracking. The averages of the errors are shown here as well as the average distance from the true measured position as calculated using Equations 3 -6…………………………………………………………...…………………….…..67 Table 4.2 Comparison of the target location and errors of the probe location for both trackers. The location of the target was taken from the images that were collected in the 2D studies with a 2% Liposyn filled cubical phantom. The true location of the target was compared to the location found in the images giving the errors shown above.……………………………………………………………………………….71 Table 4.3 Table showing the error of the acoustic, optical, and multiple objects with optical. Each of the co-registration software's accuracy was compared in a study where the probe head with the tracker attached was moved along the face of a cubical phantom. The positions at which the probe(s) head was/were located were measured physically and through the co-registration software to provide an accurate comparison of the accuracy of each tracker……………………………………………………………………….…….. A above is a large bed manufactured by Imaging Diagnostic Systems, Inc. It involves the breast to be imaged through transillumination while placed in a hole on the imaging bed. B above is also a transillumination imager that requires compression of the breast for imaging [Wang, et al, 2010]. C above is a hand held imager, however is for spectroscopic measurements [Bevilacqua, et al, 2000] [Chance, et al. 2005;Chen, et al. 2004;Sao, et a. 2003;Tromberg, et al. 2005;Xu, et al. 2007;Zhu, et al. 1999]. Recently, the Optical Imaging Laboratory (OIL) has developed a hand held optical imaging system that is capable of 3D tomography. To obtain measurements relevant for 3D tomographic imaging, a co-registration technique is employed, that allows registering the positional information of the hand-held probe on the tissue geometry during imaging studies. The feasibility of co-registered imaging and 3D tomography studies on tissue phantoms have been demonstrated in the past. [Ge, et al. 2008;Jayachandran, et al. 2007]. However, there are limitations in our hand-held optical imaging system in the path of our ongoing clinical translational efforts. These include:(i) Longer imaging times: The optical imaging system and the positional tracking device are operated independently via ...

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Hand-held based near-infrared optical imaging devices: A review

Cited by 75 publications

References 74 publications

Recent Progress of Near-Infrared (NIR) Imaging —Development of Novel Instruments and Their Applicability for Practical Situations—

Recent Progress of Near-Infrared (NIR) Imaging —Development of Novel Instruments and Their Applicability for Practical Situations—

Tissue phantom-based breast cancer detection using continuous near-infrared sensor

Performance Enhancement In Accuracy and Imaging Time of a Hand-Held Probe-Based Optical Imager

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