Handgrip Strength at Baseline and Mortality Risk in a Cohort of Women and Men on Hemodialysis: A 4-Year Study

Matos, Cácia Mendes; Silva, Luciana Ferreira; Santana, Ludmilla Dias; Santos, Larissa Silva; Protásio, Bruno Mendonça; Rocha, Mateus Teixeira; Ferreira, Vanessa Lima; Azevedo, Matheus Freitas; Martins, Márcia; Lopes, Gildete Barreto; Lopes, Antônio Alberto

doi:10.1053/j.jrn.2013.12.005

Cited by 56 publications

(49 citation statements)

References 27 publications

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“…[9][10][11][12][13] Our finding of similar associations between grip strength and all-cause mortality across age groups is in line with the few previous reports which have been able to stratify analyses by age. 14-16 19 22 23 Our finding of an equally strong inverse association between grip strength and all-cause mortality in men and women is also consistent with findings in other studies.…”

Section: Discussionsupporting

confidence: 90%

“…9 Since the publication of this review, subsequent studies have continued to find that weaker grip strength is associated with increased all-cause mortality rates in a range of settings. [10][11][12][13] Most studies of grip strength in middle and old age have investigated associations with all-cause mortality, and studies that have examined causespecific mortality are not as numerous. [14][15][16][17][18][19] Furthermore, often such studies are only powered to investigate broad groups of causes of death such as cardiovascular disease (CVD) and cancer, and have not been able to look at additional causes such as ischaemic heart disease (IHD), respiratory diseases and external causes.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The association of grip strength from midlife onwards with all-cause and cause-specific mortality over 17 years of follow-up in the Tromsø Study

Strand

Cooper

Bergland

et al. 2016

J Epidemiol Community Health

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BackgroundGrip strength has consistently been found to predict all-cause mortality rates. However, few studies have examined cause-specific mortality or tested age differences in these associations.MethodsIn 1994, grip strength was measured in the population-based Tromsø Study, covering the ages 50–80 years (N=6850). Grip strength was categorised into fifths, and as z-scores. In this cohort study, models with all-cause mortality and deaths from specific causes as the outcome were performed, stratified by sex and age using Cox regression, adjusting for lifestyle-related and health-related factors.ResultsDuring 17 years of follow-up, 2338 participants died. A 1 SD reduction in grip strength was associated with HR=1.17 (95% CI 1.12 to 1.22) for all-cause mortality in a model adjusted for age, gender and body size. This association was similar across all age groups, in men and women, and robust to adjustment for a range of lifestyle-related and health-related factors. Results for deaths due to cardiovascular disease (CVD), respiratory diseases and external causes resembled those for all-cause mortality, while for cancer, the association was much weaker and not significant after adjustment for lifestyle-related and health-related factors.ConclusionsWeaker grip strength was associated with increased all-cause mortality rates, with similar effects on deaths due to CVD, respiratory disease and external causes, while a much weaker association was observed for cancer-related deaths. These associations were similar in both genders and across age groups, which supports the hypothesis that grip strength might be a biomarker of ageing over the lifespan.

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Section: Discussionsupporting

confidence: 90%

Section: Introductionmentioning

confidence: 99%

The association of grip strength from midlife onwards with all-cause and cause-specific mortality over 17 years of follow-up in the Tromsø Study

Strand

Cooper

Bergland

et al. 2016

J Epidemiol Community Health

View full text Add to dashboard Cite

show abstract

“…2 In addition to its use in evaluation of musculoskeletal and neuromuscular disorders, 3,4 it was used as a predictive factor of postoperative complications, 5 risk of mortality in patients on hemodialysis 6 and critically ill patients. 7 Handgrip strength is "the maximal power of forceful voluntary flexion of all fingers under normal biokinetic conditions".…”

Section: Introductionmentioning

confidence: 99%

Handgrip strength in medical students: Correlation with body mass index and hand dimensions

Al-Asadi

2018

Asian J Med Sci

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Background:Handgrip is a predictor of physical fitness, hand functions, and nutritional status. It is affected by many factors including age, sex, body mass index, and hand dimensions.Aims and Objectives: To assess the handgrip strength among medical students and to examine its correlation with body mass index and hand dimensions. Materials and Methods: This cross-sectional study included 256 students of both sexes selected from College of Medicine, Basrah University, Iraq using non-probability purposive sampling method. Their anthropometric parameters including height, weight, and hand dimensions were assessed using routine techniques. The handgrip was measured by using a handheld dynamometer. Hand preference was determined by asking which hand was used to write. Results: The mean age of the participants was 21.1 ± 1.9 years. The mean of handgrip strength was 34.1 ± 11.9 Kg. Males had significantly (P <0.001) greater handgrip strength than females. Statistically significant correlation was detected between body mass index, hand dimensions and handgrip strength. The right-handed students scored significantly higher grip strength with their preferred hand. While among left-handed students, no significant difference in handgrip strength was noticed between left and right hands. Multivariate logistic regression analysis showed that gender, hand span, height, and body mass index were independent determinants of handgrip strength. They accounted for 70.6% of the variation in handgrip strength. Conclusion: A significant effect of body mass index and hand span on handgrip strength among medical students was observed.

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“…Although muscle weakness has been repeatedly reported to be associated with increased mortality in dialysis patients [19,20] , results of previous studies in dialysis patients have differed with regard to muscle wasting, with some reporting an association between muscle strength measured with HGS and body composition, whereas others found no association, or only a limited association with less than 10% of the variance in muscle strength explained by change in muscle mass [21,22] . This could be due to changes in the hydration status with dialysis [23] , depending upon whether measurements are made prior to or post-dialysis, which could potentially influence anthropomorphic measurements, DEXA scans and bioimpedance assessments [13,24] .…”

Section: Discussionmentioning

confidence: 98%

Measurement of Muscle Strength in Haemodialysis Patients by Pinch and Hand Grip Strength and Comparison to Lean Body Mass Measured by Multifrequency Bio-Electrical Impedance

Omichi¹,

Srivareerat²,

Panorchan³

et al. 2016

Ann Nutr Metab

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Background: Muscle weakness is a risk factor for mortality in haemodialysis (HD) patients; we wished to determine whether measuring the composition of the arm with bioimpedance was associated with arm muscle strength. Methods: We measured pinch strength (PS) and hand grip strength (HGS) in 250 adult HD patients with corresponding post-dialysis multifrequency bioelectrical assessments with segmental body analysis. Results: Mean age 64.0 ± 15.6, 66% male and 45.6% diabetic. The maximum HGS in the dominant or non-fistula arm was 18.9 ± 9.2 kg and PS 4.09 ± 1.96 kg respectively, with a correlation of r = 0.80, p < 0.001. HGS was associated with body cell mass (β 0.37, p < 0.001) and PS with appendicular muscle mass (β 0.06, p < 0.001). Both HGS and PS were independently associated with the ratio of extracellular water (ECW) to total body water (TBW); β -139.5, p = 0.024, β -44.8, p < 0.001 in the arm. The presence of an arterio-venous fistula increased the ECW/TBW ratio in the arm from 0.383 ± 0.009 to 0.390 ± 0.012, p < 0.05. Conclusion: Muscle strength measured by HGS and PS was associated with both markers of whole body and segmental body composition within the arm, particularly ECW/TBW. Bioimpedance measurements and assessment of muscle strength should be measured in the non-fistula arm.

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Handgrip Strength at Baseline and Mortality Risk in a Cohort of Women and Men on Hemodialysis: A 4-Year Study

Cited by 56 publications

References 27 publications

The association of grip strength from midlife onwards with all-cause and cause-specific mortality over 17 years of follow-up in the Tromsø Study

The association of grip strength from midlife onwards with all-cause and cause-specific mortality over 17 years of follow-up in the Tromsø Study

Handgrip strength in medical students: Correlation with body mass index and hand dimensions

Measurement of Muscle Strength in Haemodialysis Patients by Pinch and Hand Grip Strength and Comparison to Lean Body Mass Measured by Multifrequency Bio-Electrical Impedance

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