Handwritten Tamil character recognition

Closed-form estimations of the bistable region in metal cutting via the method of averaging

“…It must be mentioned that formula (39) associated with the power law cutting force characteristics (5) was already derived by Tamás Kalmár-Nagy in [16] and also by Pankaj Wahi according to personal communications [52]. In their works an equivalent approach, the method of harmonic balance was used.…”

Analise da expressão de ERBB2, KI-67, USP2a e acido graxo sintase (FAS) em carcinomas espinocelulares de boca

“…A direct bi-directional connection between the expression of this receptor and FAS was experimentally evidenced by Menendez et al 30 According to these authors, the inhibition of FAS expression by means of RNAi or its natural specific inhibitor cerulenin down-regulates ErbB2 mRNA in breast and ovarian cancer cell lines. 30,39 Moreover, the association of cerulenin with Trastuzumab (Herceptin) synergistically enhances apoptotic cell death in a breast cancer cell line. 39 In addition, ErbB2 overexpressing NIH-3T3 cells show high FAS protein levels and cerulenin is able to inhibit their growth in soft agar as well as to induce enhanced apoptotic cell death, in comparison with the wild type cells.…”

“…30,39 Moreover, the association of cerulenin with Trastuzumab (Herceptin) synergistically enhances apoptotic cell death in a breast cancer cell line. 39 In addition, ErbB2 overexpressing NIH-3T3 cells show high FAS protein levels and cerulenin is able to inhibit their growth in soft agar as well as to induce enhanced apoptotic cell death, in comparison with the wild type cells. 31 In the last few years, FAS expression and activity have been described as abnormally high in several human cancers, 20,[22][23][24][25][26] including OSCC, [27][28][29] and associated with poor prognosis.…”

“…The paraffin embedded samples were cut (3 m) and mounted on silane-coated glass slides for haematoxylin and eosin (H&E) staining and immunohistochemistry. Immunodetection of FAS, ErbB2, and Ki-67 was performed as previously described 7,39 . Briefly, the sections were deparaffinized, rehydrated in graded ethanol solutions and immersed in 3% H 2 O 2 for 25 min at room temperature.…”