Haptoglobin in children with infectious hepatitis

Haptoglobin Level in Some Diseases of Infancy and Childhood

“…I n the present study, there was a good c,orrelation between chronicity of the disease and the diminution in haptoglobin level. This agrees with the findings of Hever & Vadasz [2]. Cases presenting with jaundice and active hepatitis of one week or less showed a mean HbBC of 78.3 mg/100 ml serum.…”

Haptoglobin in Thalassemia

“…This protein in- creases in inflammatory, neoplastic, degenerative processes, and fol lowing steroid treatment [7,[15][16][17]. Its level is found to be low in the newborn period [18,19] and in liver diseases [17,20] and to have the effect of estrogens [21]. Although genetically determined absence of this protein is well known [22,23], in general, decrease or absence of serum Hp has been observed in chronic or acquired types of hemolytic anemias in which the Hb turnover may be more than doubled, which indicates the severity of hemolysis [1,7], Searches for Hp were made by J unnarkar [8], Badr-El-Din et al [9] and M üller-Eberhard et al [10] in 5, 7 and 3 patients with thalassemia major respectively, but none could be shown in any of them.…”

Beziehungen zwischen Haptoglobin und Serumbilirubin bei akuter Hepatitis epidemica im Kindesalter

“…Andererseits könnte die Hämoglobinbindungskapazität im Serum auf Grund der Beziehungen des Haptoglobins zum Hämoglobinstoffwechsel durch die bei der Hepatitis epidemica verstärkt auftretende Hämolyse der Erythrozyten beeinflußt werden. Außerdem sollten Vergleiche mit bekannten Haptoglobinwerten bei Leberkrankheiten angestellt werden (6).…”