2024
DOI: 10.1111/1751-7915.70032
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Harnessing Gram‐negative bacteria for novel anti‐Gram‐negative antibiotics

Joy Birkelbach,
Carsten E. Seyfert,
Sebastian Walesch
et al.

Abstract: Natural products have proven themselves as a valuable resource for antibiotics. However, in view of increasing antimicrobial resistance, there is an urgent need for new, structurally diverse agents that have the potential to overcome resistance and treat Gram‐negative pathogens in particular. Historically, the search for new antibiotics was strongly focussed on the very successful Actinobacteria. On the other hand, other producer strains have been under‐sampled and their potential for the production of bioacti… Show more

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