Harnessing multimodal wrinkle patterns in flexible films by three-axial mechanical loading

Wang, Qiaofan; Wang, Wei; Lu, Chenxi; Hu, Liang; Ni, Yong; Yu, Senjiang

doi:10.1016/j.eml.2024.102145

Extreme Mechanics Letters

2024

DOI: 10.1016/j.eml.2024.102145

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Harnessing multimodal wrinkle patterns in flexible films by three-axial mechanical loading

Qiaofan Wang,

Wei Wang,

Chenxi Lu

et al.

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Surface Deformation of Biocompatible Materials: Recent Advances in Biological Applications

Yoon,

Fuwad,

Jeong

et al. 2024

Biomimetics

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The surface topography of substrates is a crucial factor that determines the interaction with biological materials in bioengineering research. Therefore, it is important to appropriately modify the surface topography according to the research purpose. Surface topography can be fabricated in various forms, such as wrinkles, creases, and ridges using surface deformation techniques, which can contribute to the performance enhancement of cell chips, organ chips, and biosensors. This review provides a comprehensive overview of the characteristics of soft, hard, and hybrid substrates used in the bioengineering field and the surface deformation techniques applied to the substrates. Furthermore, this review summarizes the cases of cell-based research and other applications, such as biosensor research, that utilize surface deformation techniques. In cell-based research, various studies have reported optimized cell behavior and differentiation through surface deformation, while, in the biosensor and biofilm fields, performance improvement cases due to surface deformation have been reported. Through these studies, we confirm the contribution of surface deformation techniques to the advancement of the bioengineering field. In the future, it is expected that the application of surface deformation techniques to the real-time interaction analysis between biological materials and dynamically deformable substrates will increase the utilization and importance of these techniques in various fields, including cell research and biosensors.

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Surface Deformation of Biocompatible Materials: Recent Advances in Biological Applications

Yoon,

Fuwad,

Jeong

et al. 2024

Biomimetics

View full text Add to dashboard Cite

show abstract

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Harnessing multimodal wrinkle patterns in flexible films by three-axial mechanical loading

Cited by 1 publication

References 60 publications

Surface Deformation of Biocompatible Materials: Recent Advances in Biological Applications

Surface Deformation of Biocompatible Materials: Recent Advances in Biological Applications

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