2024
DOI: 10.1128/cmr.00078-24
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Harnessing the host response for precision infectious disease diagnosis

E. Wilbur Woodhouse,
Micah T. McClain,
Christopher W. Woods

Abstract: SUMMARY Detection of the presence of infection and its etiology must be accurate and timely to facilitate appropriate antimicrobial use. Diagnostic strategies that rely solely on pathogen detection often are insufficient due to poor test characteristics, inability to differentiate colonization from infection, or protracted delay to result. Understanding the human response across different pathogens on a clinical and molecular level can provide more accurate, timely, and useful answers, especially in … Show more

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