Harnessing Transformers: A Leap Forward in Lung Cancer Image Detection

Lung cancer is a leading cause of cancer-related deaths worldwide, emphasizing the significance of early detection. Computer-aided diagnostic systems have emerged as valuable tools for aiding radiologists in the analysis of medical images, particularly in the context of lung cancer screening. A typical pipeline for lung cancer diagnosis involves pulmonary nodule detection, segmentation, and classification. Although traditional machine learning methods have been deployed in the previous years with great success, this literature review focuses on state-of-the-art deep learning methods. The objective is to extract key insights and methodologies from deep learning studies that exhibit high experimental results in this domain. This paper delves into the databases utilized, preprocessing steps applied, data augmentation techniques employed, and proposed methods deployed in studies with exceptional outcomes. The reviewed studies predominantly harness cutting-edge deep learning methodologies, encompassing traditional convolutional neural networks (CNNs) and advanced variants such as 3D CNNs, alongside other innovative approaches such as Capsule networks and transformers. The methods examined in these studies reflect the continuous evolution of deep learning techniques for pulmonary nodule detection, segmentation, and classification. The methodologies, datasets, and techniques discussed here collectively contribute to the development of more efficient computer-aided diagnostic systems, empowering radiologists and dfhealthcare professionals in the fight against this deadly disease.

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GFLASSO-LR: Logistic Regression with Generalized Fused LASSO for Gene Selection in High-Dimensional Cancer Classification

Bir-Jmel,

Douiri,

Bernoussi

et al. 2024

Computers

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Advancements in genomic technologies have paved the way for significant breakthroughs in cancer diagnostics, with DNA microarray technology standing at the forefront of identifying genetic expressions associated with various cancer types. Despite its potential, the vast dimensionality of microarray data presents a formidable challenge, necessitating efficient dimension reduction and gene selection methods to accurately identify cancerous tumors. In response to this challenge, this study introduces an innovative strategy for microarray data dimension reduction and crucial gene set selection, aiming to enhance the accuracy of cancerous tumor identification. Leveraging DNA microarray technology, our method focuses on pinpointing significant genes implicated in tumor development, aiding the development of sophisticated computerized diagnostic tools. Our technique synergizes gene selection with classifier training within a logistic regression framework, utilizing a generalized Fused LASSO (GFLASSO-LR) regularizer. This regularization incorporates two penalties: one for selecting pertinent genes and another for emphasizing adjacent genes of importance to the target class, thus achieving an optimal trade-off between gene relevance and redundancy. The optimization challenge posed by our approach is tackled using a sub-gradient algorithm, designed to meet specific convergence prerequisites. We establish that our algorithm’s objective function is convex, Lipschitz continuous, and possesses a global minimum, ensuring reliability in the gene selection process. A numerical evaluation of the method’s parameters further substantiates its effectiveness. Experimental outcomes affirm the GFLASSO-LR methodology’s high efficiency in processing high-dimensional microarray data for cancer classification. It effectively identifies compact gene subsets, significantly enhancing classification performance and demonstrating its potential as a powerful tool in cancer research and diagnostics.

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Harnessing Transformers: A Leap Forward in Lung Cancer Image Detection

Cited by 3 publications

References 28 publications

CoAtNet-Lite: Advancing Mammogram Mass Detection Through Lightweight CNN - Transformer Fusion with Attention Mapping

CoAtNet-Lite: Advancing Mammogram Mass Detection Through Lightweight CNN - Transformer Fusion with Attention Mapping

Pulmonary Nodule Detection, Segmentation and Classification Using Deep Learning: A Comprehensive Literature Review

GFLASSO-LR: Logistic Regression with Generalized Fused LASSO for Gene Selection in High-Dimensional Cancer Classification

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