Having few remaining teeth is associated with a low nutrient intake and low serum albumin levels in middle-aged and older Japanese individuals: findings from the NIPPON DATA2010

Abstract

BackgroundOral health is thought to be associated with diet quality, and socioeconomic status (SES) affects both oral health and diet. The aim of this study was to investigate the association between the number of teeth and dietary intake as well as nutritional biomarker, considering the subjects’ SES.MethodsWe conducted a cross-sectional analysis of data from 2049 individuals aged ≥ 50 years from the National Integrated Project for Prospective Observation of Non-communicable Disease and its Trends in the Aged 2010. The number of remaining teeth was categorized into age-specific quartiles (Q1 to Q4). We assessed the adjusted means and 95% confidence intervals for dietary variables by the number of teeth using analysis of covariance. Stratified analyses by SES were also conducted.ResultsThe intake of grain products was 31 g higher, and those of vegetables and meat were 30 g and 8 g lower, respectively, in Q1 (fewer teeth) than in Q4 (more teeth). Carbohydrate intake was higher whereas protein, minerals (potassium, magnesium, and zinc), vitamins (vitamins A, E, B1, B6, β-carotene, and folic acid), and dietary fiber intakes were lower among individuals with fewer teeth. Adjusted mean serum albumin levels were low in Q1. The associations between the number of teeth and dietary intake were more evident in individuals with a low SES.ConclusionsHaving few remaining teeth was associated with a low nutrient intake and low serum albumin levels in middle-aged and older Japanese adults, and these associations were more evident in individuals with low SES.Electronic supplementary materialThe online version of this article (10.1186/s12199-018-0752-x) contains supplementary material, which is available to authorized users.

Self-Reported Oral Health, Oral Hygiene and Associated Factors in Lithuanian Adult Population, 1994–2014

“…A steep increase in the loss of teeth with age was also reported by other authors [13,27,28,30]. The tooth loss in adults was associated with chewing problems, lower diet quality, reduced nutrient intake and low serum albumin levels [31,32].…”

Sex differences in expression of immune elements emerge in children, young adults and mice with osteosarcoma

“…PD-L1 expression is associated with a 90% excess risk in death for OS and an elevated risk of death among males (Hazard ratio: 1.25) [ 39 ]. In vitro and in vivo studies have shown that PD-1 blockade enhances cisplatin effectiveness and may improve outcomes in humans [ 40 , 41 ]. There is much debate in the literature on sex differences in immunotherapy response with males having better outcomes than females.…”

Tooth loss leads to reduced nutrient intake in middle-aged and older Japanese individuals

“…In the paper by Nakamura et al [7], the trend for individuals with fewer remaining teeth to have worse nutrient intake was more pronounced among those with low SES. This finding suggests that SES may be intimately involved in the pathway leading from tooth loss to poor nutrient intake.…”

“…Nakamura et al [7] studied the relationship between number of teeth and nutrient intake by evaluating not only nutrient intake status obtained from a household-based dietary survey, but also serum albumin level as a nutritional biomarker. They investigated the relationship between number of teeth and nutrient intake by analyzing data from 2049 individuals ≥ 50 years old obtained from the NIPPON DATA 2010 survey.…”