Hazelnut supplementation enhances plasma antioxidant potential and lowers plasma cholesterol levels

Durak, İlker; Köksal, I T; Kaçmaz, Murat; Büyükkoçak, Serap; Çimen, Burak; Öztürk, Hasan Serdar

doi:10.1016/s0009-8981(99)00066-2

Cited by 89 publications

(80 citation statements)

References 5 publications

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“…Unlike the study by Durak et al (1999) in which there was a increase in TAG in the hazelnut supplemented diet, we found a significant (Po0.05) reduction in TAG (31.8%) after supplementation with a hazelnut-enriched diet compared with baseline ( Figure 1). Our results are in agreement with those previously published for other tree nuts (Rajaram et al, 2001;Hyson et al, 2002) and other MUFA-rich foods (Grundy, 1986;Kris-Etherton et al, 1999a).…”

Section: Effects Of Hazelnut-enriched Diet On Plasma Lipid Profiles Scontrasting

confidence: 96%

“…Hazelnut-rich MUFA diet demonstrated a 5.2% reduction in total cholesterol compared with baseline ( Figure 1). Durak et al (1999), provided about 68-69 g/day of hazelnut (1 g/day/kg body weight) in the diet of 30 healthy students and found a significant reduction (Po0.005) in their total plasma cholesterol concentrations. However, the amount of hazelnut consumed was about 30 g/day more than that used in the present study.…”

Section: Effects Of Hazelnut-enriched Diet On Plasma Lipid Profiles Smentioning

confidence: 92%

“…In contrast, there was no difference between the control diet and the baseline. The significant increase in HDL cholesterol concentrations has been reported after consumption of tree nuts such as hazelnut (Durak et al, 1999), almond (Hyson et al, 2002), pistachio (Edwards et al, 1999) and macadamia (Garg et al, 2003). It can be speculated that the increase in HDL cholesterol might be most likely due to decreased triglycerides, where HDL becomes less of a substrate for catabolism (Tokgözoglu, 1999).…”

Section: Effects Of Hazelnut-enriched Diet On Plasma Lipid Profiles Smentioning

confidence: 99%

“…However, recent epidemiologic and clinical studies suggest that frequent nut consumption is associated with favorable plasma lipid profiles (Durak et al, 1999;Edwards et al, 1999;Kris-Etherton et al, 1999b;Zambó n et al, 2000;Rajaram et al, 2001;Hyson et al, 2002;Garg et al, 2003) and reduced risk of coronary heart disease (CHD), cardiovascular disease (CVD), myocardial infarction, atherosclerosis and other chronic ailments (Fraser et al, 1992;Hu and Stampfer, 1999;Sabaté et al, 2000;Albert et al, 2002;Feldman, 2002). The FDA (2003) has recently authorized a health claim about the relationship between the consumption of nuts and reduced risk of CHD.…”

Section: Introductionmentioning

confidence: 99%

“…Few studies have been carried out using hazelnut-enriched diet (Alphan et al, 1997;Durak et al, 1999). Therefore, little is known about how MUFA-rich hazelnut might affect the plasma lipid response to a cholesterol-lowering diet.…”

Section: Introductionmentioning

confidence: 99%

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Effects of hazelnut-enriched diet on plasma cholesterol and lipoprotein profiles in hypercholesterolemic adult men

Mercanlıgil

Arslan

Alasalvar³

et al. 2006

Eur J Clin Nutr

105

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Objective: Frequent consumption of nuts is associated with favorable plasma lipid profiles and reduced risk of coronary heart disease (CHD). This study was conducted to investigate the effects of hazelnut-enriched diet on plasma cholesterol and lipoprotein profiles in hypercholesterolemic adult men compared with baseline and control diet, and also to measure the anthropometric parameters, habitual physical activities, nutrient intake and endothelial function. Subjects and design: Fifteen hypercholesterolemic men aged 4878 years were recruited voluntarily. A well-controlled, 2-period (P 1 and P 2 ) study design with a total of 8-week was implemented. In the P 1 , subjects consumed a control diet (low-fat, low-cholesterol and high-carbohydrate). During the P 2 , the control diet was supplemented with MUFA-rich hazelnut (40 g/day), which provided 11.6% of total energy content. Anthropometric parameters and habitual physical activities were recorded. Plasma total and HDL cholesterol, TAG, ApoA-1, Apo B, total homocysteine and glucose concentrations were measured. All parameters and measurements were obtained at baseline and end of each 4-week diet period. Results: Body weights of subjects remained stable throughout the study. Compared with baseline, the hazelnut-enriched diet decreased (Po0.05) the concentrations of VLDL cholesterol, triacylglycerol, apolipoprotein B by 29.5, 31.8, and 9.2%, respectively, while increasing HDL cholesterol concentrations by 12.6%. Total/HDL cholesterol and LDL/HDL cholesterol ratios favorably decreased (Po0.05). Although insignificant there was a decreasing trend for the rest of parameters, particularly in total (5.2%) and LDL cholesterol (3.3%) in subjects consuming a hazelnut-enriched diet compared to that of the baseline. No changes were found in fasting levels of glucose, Apo A-1 and homocysteine between the control and hazelnut-enriched diets. Conclusions: This study demonstrated that a high-fat and high-MUFA-rich hazelnut diet was superior to a low-fat control diet because of favorable changes in plasma lipid profiles of hypercholesterolemic adult men and, thereby positively affecting the CHD risk profile. Sponsorship:

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