Head and Neck Radiology in AAV

Abstract

G ranulomatosis with polyangiitis (GPA), which is a rare antineutrophil cytoplasmic antibody (ANCA) associated autoimmune disease, frequently (70% to 100%) involves ear, nose and throat. Imaging characteristics of sinonasal involvement are well described by computed tomography (CT) scans and includes mucosal thickening, osseous erosions or destructions and neoosteogenesis [1][2][3][4].Although nodular thickening may suggest GPA, mucosal thickening is frequent but mostly a nonspesific finding that could be seen in various etiologies of sinusitis [4]. On the other hand, bony changes such as erosions/destructions and neoosteogenesis is highly suggestive of GPA, especially when clinical suspicion is high [1, 2] (Figure 1).