Head and neck soft tissue sarcomas of adult: prognostic value of surgery in multimodal therapeutic approach

Penel, Nicolas; Haverbeke, Christophe Van; Lartigau, Éric; Vilain, M O; Van, J. Ton; Mallet, Y.; Lefebvre, Jean‐Louis

doi:10.1016/j.oraloncology.2004.04.001

Cited by 53 publications

(43 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Misjudgment and late diagnosis may seriously affect treatment outcome. In patients with soft-tissue sarcomas, survival after 5 years ranges from 46% to 71% in the primary or metastasis condition of the disease [6,8,9]. Only 53 cases of oral angiosarcomas were reported in the literature by 1986.…”

Section: Discussionmentioning

confidence: 99%

“…Primary or metastatic diagnosis of angiosarcoma occurs only in 4% of the pharynx, oral cavity or paranasal sinuses [14]. In the literature the prognosis factor is based on size, depth and grade of the tumors and the overall prognosis is very poor [8][9][10][11][12][13][14][15].…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, soft-tissue sarcomas are classified as grades in a three-scale system (necrosis, differentiation and mitosis rate) and it has been shown that the 3-year survival rate decreases drastically in compareson of grade 1 -3 where 3 represents the lowest chance of metastasis free survival [6][7][8][9][10][11][12][13][14][15][16].…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Angiosarcoma of the mandible: Metastasis from a primary tumor of the right atrium of the heart

Ramadhan¹,

Willén²,

Thor³

2013

CRCM

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Angiosarcoma of the mandible: Metastasis from a primary tumor of the right atrium of the heart

Ramadhan¹,

Willén²,

Thor³

2013

CRCM

View full text Add to dashboard Cite

show abstract

“…Literature shows survey studies involving head and neck sarcoma [5,[8][9][10][11][12][52][53][54][55][56][57][58][59][60][61][62][63][64] which investigate patient profile and disease prognosis. In this study, in 20 years, the frequency of malignant head and neck neoplasms is about 1 every 2 years.…”

Section: Discussionmentioning

confidence: 99%

Diagnosis and Treatment of Head and Neck Sarcomas: Personal Experiences

Laus¹

2013

JCTR

View full text Add to dashboard Cite

Sarcomas are a rare group of tumors. They do not commonly manifest as malignancies in the head and neck region. The rare nature of these tumors has resulted in a limited number of publications. This is a descriptive study. We included patients with primary sarcomas of the head and neck, observed between 1991 and 2011 in the department of Otorhinolaryngology (University of Chieti, Italy). We studied the following variables: age, gender, race, origin, primary anatomical location of the neoplasm, pathology, diagnosis and type of cancer treatment employed. During the study period, we found 9 patients with head and neck sarcomas. Of this sample, 6 were males, and 3 were females. The man/woman ratio was 2:1. As far as age is concerned, the most affected age range was between 60 and 80 years. The mean age of the patients was 62. As far as pathology is concerned, we found 7 histopathological variations of sarcomas, and the most common type was the leiomyosarcoma. The most widely used treatment modality was surgical treatment. The data in this study show that head and neck sarcomas are rare tumors with high histological variability, which may involve different anatomical sites. Since these are rare and not well-known lesions, further epidemiological studies must be carried out, in order to give us more knowledge about the disease.

show abstract

“…Surgery is the primary treatment for these types of tumors (10). The first surgical procedure is crucial, as the small size of the tumor is accompanied by the absence of post-surgery and postradiotherapy fibrosis, which facilitates the surgery.…”

Section: Discussionmentioning

confidence: 99%

The acromion thoracic flap: A reconstructive resource after exeresis of a parotid fibrosarcoma

Bonet¹,

Zapater²,

Alba³

et al. 2011

Med Oral

View full text Add to dashboard Cite

Sarcomas are rather uncommon in the salivary glands and have a high tendency towards recurrence. The treatment of choice is surgery, with the first surgical procedure being crucial, as the small size of the tumor is accompanied by the absence of post-surgery and post-radiotherapy fibrosis, which facilitates the surgery. The evident tendency towards recurrence makes it advisable to be radical in the exeresis. Often we have to consider a reconstructive period. Negative surgical margins increases the rates of local control. Treatment with radiotherapy is the complementary treatment indicated for patients with surgical margins less than 2 mm or positive. It has been observed that this treatment improves the local control of the illness. We present a case of parotid fibrosarcoma of a low grade of malignancy that was treated by means of parotidectomy and post-operative radiotherapy. The patient presented up to three recurrences, one of which required an acromion thoracic flap in order to reconstruct the surgical defect. Despite the treatment, the patient ended up dying because one of the recurrences was not operable.

show abstract

Head and neck soft tissue sarcomas of adult: prognostic value of surgery in multimodal therapeutic approach

Cited by 53 publications

References 21 publications

Angiosarcoma of the mandible: Metastasis from a primary tumor of the right atrium of the heart

Angiosarcoma of the mandible: Metastasis from a primary tumor of the right atrium of the heart

Diagnosis and Treatment of Head and Neck Sarcomas: Personal Experiences

The acromion thoracic flap: A reconstructive resource after exeresis of a parotid fibrosarcoma

Contact Info

Product

Resources

About