Health promoting functional lipids from microalgae pool: A review

Katiyar, Richa; Arora, Amit

doi:10.1016/j.algal.2020.101800

Cited by 126 publications

(41 citation statements)

References 124 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Microalgae are considered a sustainable source of essential and bioactive lipids [1]. Moreover, they are quite diverse in their fatty acid (FA) profile and abundances, which shows exploitable potential [2].…”

Section: Introductionmentioning

confidence: 99%

Microalgae as Sustainable Bio-Factories of Healthy Lipids: Evaluating Fatty Acid Content and Antioxidant Activity

et al. 2021

View full text Add to dashboard Cite

The demand for sustainable and environmentally friendly food sources and food ingredients is increasing, and microalgae are promoted as a sustainable source of essential and bioactive lipids, with high levels of omega-3 fatty acids (ω-3 FA), comparable to those of fish. However, most FA screening studies on algae are scattered or use different methodologies, preventing a true comparison of its content between microalgae. In this work, we used gas-chromatography mass-spectrometry (GC-MS) to characterize the FA profile of seven different commercial microalgae with biotechnological applications (Chlorella vulgaris, Chlorococcum amblystomatis, Scenedesmus obliquus, Tetraselmis chui, Phaeodactylum tricornutum, Spirulina sp., and Nannochloropsis oceanica). Screening for antioxidant activity was also performed to understand the relationship between FA profile and bioactivity. Microalgae exhibited specific FA profiles with a different composition, namely in the ω-3 FA profile, but with species of the same phylum showing similar tendencies. The different lipid extracts showed similar antioxidant activities, but with a low activity of the extracts of Nannochloropsis oceanica. Overall, this study provides a direct comparison of FA profiles between microalgae species, supporting the role of these species as alternative, sustainable, and healthy sources of essential lipids.

show abstract

Section: Introductionmentioning

confidence: 99%

Microalgae as Sustainable Bio-Factories of Healthy Lipids: Evaluating Fatty Acid Content and Antioxidant Activity

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Because natural products have high physiological effects and low or no toxicity, recently, ingredients from natural sources have tended to dominate the cosmetic market. Seaweeds are rich in natural bioactive compounds such as polysaccharides, pigments, lipids, and peptides, which possess extensive health benefits to humans [ 14 , 15 , 16 ]. In particular, the ingredients from edible or cultivable seaweeds have caught the attention of the nutraceutical, pharmaceutical, and cosmeceutical industries [ 17 , 18 ].…”

Section: Introductionmentioning

confidence: 99%

Anti-Photoaging and Anti-Melanogenesis Effects of Fucoidan Isolated from Hizikia fusiforme and Its Underlying Mechanisms

Wang

Kim

et al. 2020

Marine Drugs

View full text Add to dashboard Cite

Previous studies suggested that fucoidan with a molecular weight of 102.67 kDa, isolated from Hizikia fusiforme, possesses strong antioxidant activity. To explore the cosmeceutical potential of fucoidan, its anti-photoaging and anti-melanogenesis effects were evaluated in the present study. The anti-photoaging effect was investigated in ultraviolet (UV) B-irradiated human keratinocytes (HaCaT cells), where fucoidan effectively reduced the intracellular reactive oxygen species level and improved the viability of the UVB-irradiated cells without any cytotoxic effects. Moreover, fucoidan significantly decreased UVB-induced apoptosis in HaCaT cells by regulating the protein expression of Bax, Bcl-xL, PARP, and Caspase-3 in HaCaT cells in a concentration-dependent manner. The anti-melanogenesis effect of fucoidan was evaluated in B16F10 melanoma cells that had been stimulated with alpha-melanocyte-stimulating hormone (α-MSH), and fucoidan treatment remarkably inhibited melanin synthesis in α-MSH-stimulated B16F10 cells. Further studies indicated that fucoidan significantly suppressed the expression of tyrosinase and tyrosinase-related protein-1 and -2 (TRP-1 and-2) in B16F10 cells by down-regulating microphthalmia-associated transcription factor (MITF) through regulation of the ERK–MAPK (extracellular signal regulated kinase-mitogen activated protein kinase) pathway. Taken together, these results suggest that fucoidan isolated from H. fusiforme possesses strong anti-photoaging and anti-melanogenesis activities and can be used as an ingredient in the pharmaceutical and cosmeceutical industries.

show abstract

“…Algae contain most of the plant lipids such as glycosylglycerides and phosphoglycerides [ 37 ]. Microalgae lipid content varies from 1 to 40%, and it may rise to 85% of total dry weight depending upon nutrient composition, temperature, light flux, and CO 2 concentration [ 38 ]. Storage lipids (triacylglycerols) are produced via photosynthesis and stored in cells, whereas fats involved in cell structure and metabolism are known as structural lipids (monounsaturated fatty acids (MUFA) and poly monounsaturated fatty acids (PUFA)).…”

Section: Bioactive Compoundsmentioning

confidence: 99%

Microalgal Cell Biofactory—Therapeutic, Nutraceutical and Functional Food Applications

Kiran

Mohan

2021

Plants

View full text Add to dashboard Cite

Microalgae are multifaceted photosynthetic microorganisms with emerging business potential. They are present ubiquitously in terrestrial and aquatic environments with rich species diversity and are capable of producing significant biomass. Traditionally, microalgal biomass is being used as food and feed in many countries around the globe. The production of microalgal-based bioactive compounds at an industrial scale through biotechnological interventions is gaining interest more recently. The present review provides a detailed overview of the key algal metabolites, which plays a crucial role in nutraceutical, functional foods, and animal/aquaculture feed industries. Bioactive compounds of microalgae known to exhibit antioxidant, antimicrobial, antitumor, and immunomodulatory effects were comprehensively reviewed. The potential microalgal species and biological extracts against human pathogens were also discussed. Further, current technologies involved in upstream and downstream bioprocessing including cultivation, harvesting, and cell disruption were documented. Establishing microalgae as an alternative supplement would complement the sustainable and environmental requirements in the framework of human health and well-being.

show abstract

Health promoting functional lipids from microalgae pool: A review

Cited by 126 publications

References 124 publications

Microalgae as Sustainable Bio-Factories of Healthy Lipids: Evaluating Fatty Acid Content and Antioxidant Activity

Microalgae as Sustainable Bio-Factories of Healthy Lipids: Evaluating Fatty Acid Content and Antioxidant Activity

Anti-Photoaging and Anti-Melanogenesis Effects of Fucoidan Isolated from Hizikia fusiforme and Its Underlying Mechanisms

Microalgal Cell Biofactory—Therapeutic, Nutraceutical and Functional Food Applications

Contact Info

Product

Resources

About