Heart rate variability and increased risk for developing type 2 diabetes mellitus

Abstract

The obtained results suggest that even slightly elevated risk for developing diabetes mellitus may be related to impaired HRV.

Heart rate variability based on risk stratification for type 2 diabetes mellitus

“…Therefore, this is the first study to include the moderate risk (score 12 to 14) and the high risk (score 15 to 20) groups in the HRV analysis based on linear and nonlinear indexes. The methods used were different, since in the study by Penčić-Popovic et al, 8 the ECG was used for 24 hours, while in the present study a Polar S810i was used for 5 minutes, at rest. These measurements at rest correlate and agree with the circadian variation described in the ECG.…”

“… 17 - 20 To date, only one study has correlated FINDRISC risk of developing T2DM with HRV measurements. 8 Penčić-Popović et al 8 analyzed only two groups − low risk (score <7) and slightly elevated risk (score 7-11) −, based on linear indexes. Therefore, this is the first study to include the moderate risk (score 12 to 14) and the high risk (score 15 to 20) groups in the HRV analysis based on linear and nonlinear indexes.…”

“…The HF component acts in HRV, reflecting parasympathetic modulation, while the LF component includes sympathetic and parasympathetic function, and the VLF reflects parasympathetic and neuroendocrine modulation. 8 …”

“…Penčić-Popović et al 8 were the pioneers in showing that the group classified as slightly elevated risk for T2DM (score 12; FINDRISC≥7; n=39) already had changes in linear HRV parameters (time and frequency domain) when compared to the low risk group (FINDRISC<7; n=30). These authors did not include individuals with moderate, high and very high risk, or analysis of nonlinear methods.…”

Findrisc, Utility in the Screening of Diabetes, Personalization and Associations

“…En el estudio realizado por Penčić-Popović B, Ćelić V, Ćosić Z, Pavlović-Kleut M, Čaparević Z, Kostić N, et al 14…”