Heat shock protein 60 expression in heart, liver and kidney of broilers exposed to high temperature

Yan, Jianyan; Bao, Endong; Yu, Jimian

doi:10.1016/j.rvsc.2008.09.002

Cited by 54 publications

(34 citation statements)

References 28 publications

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“…Both high-temperature exposure and low-dose ASA pretreatment have been well described to be able to induce HspB1 (Amberger et al 1999;Ebert et al 2005;SandovalMontiel et al 2013;Yan et al 2009;Yu et al 2009). Less notable, but no less meaningful, was the finding that instead of a stably variation, the increasing tendency of HspB1 fluctuated as the experiment proceeded under different treatments.…”

Section: Discussionmentioning

confidence: 99%

“…Annual losses in the USA alone was estimated at $2.4 billion due to non-protection from heat exposure ($897 million, $369 million, $299 million, and $128 million for dairy, beef, swine, and poultry industries, respectively) (N. R. St-Pierre* 2003). Heat stress leads to dysfunction in multiple organs, including the heart, one of the most important organs in multicellular organisms (Yan et al 2009). Such myocardial injury is believed to be responsible for sudden death induced by heat stress (Ellis 1972;Scheers-Masters et al 2004).…”

Section: Introductionmentioning

confidence: 99%

“…In fact, due to feather cover, lack of perspiratory glands and fast growth in modern commercial breeding facilities, poultry species, such as broiler chickens are more defenseless to high temperatures than mammals (N. R. St-Pierre* 2003;Piestun et al 2013). Many important organs displayed damages in chickens after acute heat stress exposure, including the heart (Yan et al 2009). Such injuries will change the permeability of the myocardial cell membrane and cause the release of a series of enzymes such as creatine kinase-MB (CK-MB) and lactate dehydrogenase (LDH) (Saravanan et al 2013).…”

Section: Introductionmentioning

confidence: 99%

“…Such injuries will change the permeability of the myocardial cell membrane and cause the release of a series of enzymes such as creatine kinase-MB (CK-MB) and lactate dehydrogenase (LDH) (Saravanan et al 2013). Increases of these myocardial cell damage-related enzymes have been clearly detected after heat stress (Tang et al 2013;Yan et al 2009). Moreover, heat stress exposure leads to obvious pathological changes.…”

Section: Introductionmentioning

confidence: 99%

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In vitro evaluation of aspirin-induced HspB1 against heat stress damage in chicken myocardial cells

Zhang

et al. 2016

Cell Stress and Chaperones

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To understand the potential association of heat stress resistance with HspB1 induction by aspirin (ASA) in chicken myocardial cells, variations of HspB1 expression and heat stressed-induced damage of myocardial cells after ASA administration were studied in primary cultured myocardial cells. Cytopathological lesions as well as damage-related enzymes, such as creatine kinase-MB (CK-MB) and lactate dehydrogenase (LDH), indicated the considerable protective ability of ASA pre-treatment against acute heat stress. Immunostaining assays showed that heat stress caused HspB1 to relocate into the nucleus, while ASA did not. ELISA analysis, revealed that HspB1 expression induced by ASA averaged 45.62-fold higher than that of the control. These results indicated that the acute heat-stressed injuries were accompanied by comparatively lower HspB1 expression caused by heat stress in vitro. ASA pretreatment induced a level of HspB1 presumed to be sufficient to protect myocardial cells from acute heat stress in the extracorporal model, although more detailed mechanisms will require further investigation.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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In vitro evaluation of aspirin-induced HspB1 against heat stress damage in chicken myocardial cells

Zhang

et al. 2016

Cell Stress and Chaperones

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“…This might be due to the increased metabolic activity of the heart in exposed chicks. Increased expression of Hsp 60, 90 and 70 in heart was observed in heat-exposed chicks after 2 h heat exposure and led to the localization of Hsps in myocardial tissue (Yan et al 2009). The localization of Hsps in myocardial cells during the pre-exposure might have enhanced the expression levels in heart in the present study also.…”

Section: Discussionmentioning

confidence: 99%

Effect of increased incubation temperature onHsp90 and 60 gene expressions in coloured broiler chickens

Rajkumar

Vinoth

Shanmugam

et al. 2016

Journal of Applied Animal Research

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The mRNA expression profiles of Hsp-90 alpha, Hsp-90 beta and Hsp-60 were evaluated in coloured broiler chickens, that is, Punjab broiler-2 (PB-2) and naked neck (NN), exposed to 2°C increased incubation temperature for 3 h each on 16th, 17th and 18th days of incubation. Another set of eggs were incubated at normal conditions that were utilized as control. A total of 432 chicks, 216 in each breed (PB-2; NN) and treatment (heat exposed; normal), randomly distributed were reared at high ambient temperatures (32-45°C) during summer in battery brooders. Birds were sacrificed on 0 and 28th days post-hatch and different tissues (heart, liver, muscle, spleen and bursa) were collected to assess the mRNA expression. Heat exposure during incubation significantly (P ≤ .05) influenced the expression of Hsp-90 alpha in spleen of day old; in heart, liver and spleen at 28 days in PB-2 chicken. Hsp-90 alpha mRNA expression was not significant among the tissues at different ages in NN chicken. Hsp-90 beta did not show any significant variations in gene expression across the tissues at both the age groups either in NN or in PB-2 chicken. Heat exposure had significant effect in the expression patterns of Hsp-60 at 28 days in heart, liver and spleen in PB-2 chicken. The mRNA expression of all the three genes significantly (P ≤ .05) varied in different tissues across the age groups in both PB-2 and NN chickens. The study concluded that thermal adaptation during the embryonic stage to higher incubation temperature reduced Hsp gene expression in different tissues in postnatal life during high ambient temperature which might result in increased heat tolerance capacity of the broiler chickens. ARTICLE HISTORY

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Schisandra chinensis Prevents Hepatic Lipid Peroxidation and Oxidative Stress in Rats Subjected to Heat Environmental Stress

Kim

Yoon

Hong

et al. 2012

Phytotherapy Research

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Increases in temperature cause a proliferation of heat-stress-related disorders by disrupting the body's homeostasis system, particularly when excessive levels of reactive oxygen species disrupt the balance of antioxidant defence systems. Thus, controlling oxidative stress is important for the regulation of body homeostasis. Schisandra chinensis (SC) has a potential effect on antioxidants and is resistant to high temperatures. However, the mechanism of SC during heat stress is unclear. Therefore, we evaluated the effect of SC on heat stress by performing several bioactive genetic assays on Sprague Dawley (SD) rats. The results demonstrated that heat stress significantly increased in heat-stress-related gene expression whereas it was dramatically reduced in the gene expression of the SC group. The genes related to oxidative stress were also significantly suppressed in the SC group compared with those of the heat stress group. Furthermore, there was a greater decrease in the MDA content of the SD rats in the orally administered SC group than in the heat exposure group. Thus, we demonstrate that SC has a protective effect on heat stress as a result of its strong antioxidant properties and the prevention of lipid peroxidation.

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Heat shock protein 60 expression in heart, liver and kidney of broilers exposed to high temperature

Cited by 54 publications

References 28 publications

In vitro evaluation of aspirin-induced HspB1 against heat stress damage in chicken myocardial cells

In vitro evaluation of aspirin-induced HspB1 against heat stress damage in chicken myocardial cells

Effect of increased incubation temperature onHsp90 and 60 gene expressions in coloured broiler chickens

Schisandra chinensis Prevents Hepatic Lipid Peroxidation and Oxidative Stress in Rats Subjected to Heat Environmental Stress

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