The crack growth of transparent materials after laser wavelength irradiation was studied. It is known that laser irradiation is used in many applications for the ablation of undesired material and/or coatings. The impact of laser irradiation on cracks was studied using the digital holography (DH) technique. Transparent samples were irradiated using near-ultraviolet, visible, near-infrared, and infrared light. The DH system is able to detect cracks and crack growth of the transparent samples irradiated by a range of laser wavelengths. Results also show that light with infrared to near-infrared wavelengths has a great effect on crack growth. High-resolution photomechanical effects of laser irradiation on material expansion or/and generation of defects due to specific wavelengths are also illustrated. The DH system with a multispectral laser has practical applications for laser cleaning of painted artworks.