Heavy-ion energy loss

Sofield, C.J.

doi:10.1016/0168-583x(90)90924-j

Cited by 2 publications

(2 citation statements)

References 22 publications

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“…In comparison to X-rays and γ-rays, heavy ion beam irradiation at both low and high energy has three significant properties. First, energy deposition from heavy ions mainly occurs near the end of the path when traveling through matter 1 2 3 . Second, a heavy ion has high linear energy transfer (LET) 4 5 6 , especially at the peak of the Bragg curve.…”

mentioning

confidence: 99%

“…Mid-high energy heavy ions could be used in novel radiotherapies aimed to disrupt deep-seated tumors, based on the breakout-peak of the Bragg curve 21 22 23 24 25 26 , while these ions could also be used to explore safe measures against space irradiation of astronauts during space travel 27 28 29 . In terms of inducing mechanisms, in addition to energy (mass) deposition 1 2 3 , mid-high heavy ion beams that travel through matter are also characterized by charge exchange, momentum transfer, and secondary irradiation 30 31 32 33 34 35 . Although different biological effects are observed in both the axial and radial directions along the path of heavy ion beams, the biological effects of heavy ion beams along the radial direction have yet to be well elucidated.…”

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confidence: 99%

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Three dimensional approach to investigating biological effects along energetic ion beam pathways

Sun

Wang

et al. 2017

Sci Rep

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Heavy ion beams have many exciting applications, including radiotherapy of deep-seated tumors and simulation tests of space irradiation for astronauts. These beams often use a feature that concentrates the energy deposition largely along the end of the energy pathway, leading to different distributions of biological effects along the axial direction. Currently, there is relatively little information regarding the radial directional difference of biological effects along the heavy ion paths. This study utilized a filter membrane that was quantatively applied with cells to demonstrate a 3D distribution model of irradiation on biological effects in living organisms. Some results have indicated that there is excitatory effect on the non-irradiated regions with energetic ions, which may give new insights into the distribution of biological effects along the paths of heavy ion beams with mid-high energy.

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