Helicobacter muricola sp. nov., a novel Helicobacter species isolated from the ceca and feces of Korean wild mouse (Mus musculus molossinus)

Abstract

A slowly growing microaerophilic Helicobacter strain was isolated from the ceca and fecal pellets of Korean wild mice (Mus musculus molossinus). This bacterial strain possessed a pair of nonsheathed bipolar flagella, was positive for urease, catalase and oxidase, and reduced nitrate to nitrite. It proved susceptible to nalidixic acid and resistant to cephalodine, and did not hydrolyze hippurate. On the basis of phenotypic characteristics and 16S rRNA gene sequence analysis, the isolate represents a new species of the genus Helicobacter, for which the name Helicobacter muricola sp. nov. is proposed; the type strain of the new species is w‐06T (GenBank accession number AF264783).

Helicobacter marmotae and novel Helicobacter and Campylobacter species isolated from the livers and intestines of prairie dogs

“…We have also previously documented Helicobacter species in Chilean females with chronic cholecystitis and cholesterol gallstones (Fox et al, 1998). Others have documented Helicobacter species in a variety of hepatobiliary diseases in humans (reviewed by Pellicano et al, 2008 Parker et al, 2009;Won et al, 2002). H. hepaticus, Helicobacter apodemus, Helicobacter canadensis and H. winghamensis were identified by partial 16S rRNA gene sequence analysis, suggesting that enteric Helicobacter infections may be widespread in wild rodents in China (Goto et al, 2004).…”

“…H. hepaticus, Helicobacter apodemus, Helicobacter canadensis and H. winghamensis were identified by partial 16S rRNA gene sequence analysis, suggesting that enteric Helicobacter infections may be widespread in wild rodents in China (Goto et al, 2004). H. muricola was isolated and characterized in Korean wild mice (Won et al, 2002). Comunian et al (2006) also detected Helicobacter DNA by PCR in faeces of wild rodents in Brazil.…”

“…In humans, Helicobacter pylori causes peptic ulcers and, because of its association with gastric adenocarcinoma, is classified as a class I carcinogen by the World Health Organization (Fox & Wang, 2007). In recent years, enterohepatic Helicobacter species have also been isolated from wild and laboratory rodents (Comunian et al, 2006;Fox et al, 2002Fox et al, , 2010Franklin et al, 1996;Goto et al, 2004;Won et al, 2002;Zenner, 1999).…”

The Family Helicobacteraceae

“…MIT 99-5501 AF333338 ''Helicobacter magdeburgensis'' Mice HM007-1 EF990624 Traverso et al 2010 ''Helicobacter muricola'' Mice w-06 AF264783 Won et al 2002 ''Helicobacter suncus'' Musk Shrews Kaz-1 AB006147 Goto et al 1998 ''Helicobacter westmeadii'' Human Helicobacter sp. U44756 Trivett Moore et al 1997 ''Helicobacter winghamensis'' Human NLEP 97-1090 AF246984 Melito et al 2001 The Family Helicobacteraceae…”

“…''Helicobacter muricola'' was isolated from the cecum and feces of Korean wild mice (Mus musculus molossinus) (Won et al 2002). The organism measures 0.4-0.5 mm in width by 2-5.5 mm in length, with the same morphology as other enterohepatic helicobacters such as H. typhlonius, H. hepaticus and H. rodentium.…”