Hematologic and hematopoietic response to burn injury

Posluszny, Joseph A.; Gamelli, Richard L.; Shankar, Ravi

doi:10.1016/b978-1-4377-2786-9.00023-0

Cited by 3 publications

(3 citation statements)

References 285 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…14 In humans, anemia and leukocytosis have been frequently reported within 6 to 24 h after a burn injury, 15 nonetheless, in general, leukocytosis occurs during the first 24-48 h after the injury, and it depends on the size of the burn wound, having a higher degree of leukocytosis with larger burns. 7 Hence, we think that because hematology was performed in the first 24 h after the event, hematological changes have not occurred yet.…”

Section: Discussionmentioning

confidence: 99%

“…Blood values can be a very useful tool to get a better understanding of the general condition of the patients and to better understand the damage that was caused by the electricity. 7 Muscle damage, secondary renal damage, and glucose impaired metabolism have been reported in electrocuted and burned patients. 8 Electrocution events are commonly described in different raptor species as well as several mammals, 2,4,9 plus many case reports on humans.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Blood analytes of electrocuted mantled howler monkeys (Alouatta palliata) in the Nicoya peninsula of Costa Rica

Sánchez-Murillo

Arguedas

2021

J of Medical Primatology

View full text Add to dashboard Cite

Several species of Costa Rican wildlife are suffering terrible injuries along the power lines and transformers in rural areas of the country.The most susceptible species of wildlife like monkeys, sloths, kinkajous, and squirrels are being electrocuted (and most of the time killed) because of this situation. 1 The increasing human development in rural areas and the continuous building of properties carry the need for electricity, but this has also brought the problem of poorly designed electric infrastructure. Arboreal mammals find their normal tree routes cut down so that the only way for them to cross is to get down to the ground and cross the street (where they can suffer

show abstract

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Blood analytes of electrocuted mantled howler monkeys (Alouatta palliata) in the Nicoya peninsula of Costa Rica

Sánchez-Murillo

Arguedas

2021

J of Medical Primatology

View full text Add to dashboard Cite

show abstract

“…Furthermore, extensive endothelial impairment ignites coagulation cascade, which intimately intertwined with inflammation reaction following the thermal injury and during infection [4]. And along with the wound recovery, coagulopathy is less related to burn injury but more likely owe to sepsis [5]. In our case, patients’ coagulation status was kept normal at the time of transferring to our burn center and the following 2 weeks, even if the patient had been suffering from severe wound and bloodstream infection since PBD 13.…”

Section: Discussionmentioning

confidence: 99%

Hypocoagulation induced by broad-spectrum antibiotics in extensive burn patients

Liu

et al. 2019

Burns &Amp; Trauma

View full text Add to dashboard Cite

Background Patients with extensive burns usually develop pro-coagulation soon after the injury if there is no sepsis occurred. We describe the case of an extensive burn adult suffering from hypocoagulation not related to sepsis, but secondary to antibiotic treatment. Case presentation Here, we report a case of an adult male patient suffering from flame burns of 45% total body surface area (40% full thickness) combined with inhalation injury. Hypocoagulopathy with soaring prolonged activated partial thromboplastin time value occurred on third week post-burn while systemic infection had been under control by application of broad-spectrum antibiotics. Investigations showed that not the infection but vitamin K-related coagulation factor deficiency were responsible for unexpected bleeding. However, supplemental vitamin K was not the key as we expected, which prompted us trying to decode the underlying cause of coagulation disturbance in this patient and pick out the most effective treatment for live-saving. After the withdrawal of highly suspected broad-spectrum antibiotic, Meropenem®, disturbed vitamin K related coagulation factors gradually restored to their optimal levels so as to maintain normal coagulation status. Therefore, surgical procedures without further risk of bleeding could be carried out in time for wound recovery. The patient was discharged on post-burn day 67 and transferred to a secondary hospital for his rehabilitation. Conclusion Hypocoagulopathy may be devoted to different reasons other than sepsis in extensive burns. Early recognition of the cause for coagulation disturbance is critical to make appropriate treatment and save patients’ lives. This case illustrated the importance of unveiling the mist cause for coagulation disturbance occurred in extensive burn patient, which paved the way for optimal life-saving treatments. And we also recommend burn surgeons to be alerted to antibiotic-induced vitamin K deficiency-related coagulopathy among critical burn patients.

show abstract

Squamous Cell Carcinoma at Split Thickness Skin Graft Donor Site: A Case Report and Review of the Literature

McCormick

Miotke

2022

Journal of Burn Care &Amp; Research

View full text Add to dashboard Cite

Squamous cell carcinoma (SCC) or keratoacanthoma (KA) development at split thickness skin graft donor sites is a documented but very rare entity. We describe a case in which a patient develops a lesion at his graft site seven weeks postoperatively. Upon pathological review, it was found to be SCC and was excised expediently thereafter. Notably, in reviewing the literature, these lesions tend to develop soon after the trauma of skin graft harvest with over half diagnosed within three months and a vast majority within one year of the operation. This is in contrast to Marjolin ulcers which take years to develop after the initial burn insult. Given the diversity of autograft indications in the reviewed literature, it seems unlikely that the burns themselves contribute to the development of SCC at the donor site. Our case highlights the need for routine surveillance of graft donor sites postoperatively with an emphasis on catching malignant sequelae.

show abstract

Hematologic and hematopoietic response to burn injury

Cited by 3 publications

References 285 publications

Blood analytes of electrocuted mantled howler monkeys (Alouatta palliata) in the Nicoya peninsula of Costa Rica

Blood analytes of electrocuted mantled howler monkeys (Alouatta palliata) in the Nicoya peninsula of Costa Rica

Hypocoagulation induced by broad-spectrum antibiotics in extensive burn patients

Squamous Cell Carcinoma at Split Thickness Skin Graft Donor Site: A Case Report and Review of the Literature

Contact Info

Product

Resources

About