Hemodynamic and oxygen delivery-consumption changes during partial liver resection

Abstract

The effects of partial liver resection on hemodynamics and the oxygen delivery-consumption relationship were evaluated in ten patients with hepatocellular carcinoma. The cardiac index and oxygen delivery were increased significantly (P < 0.05) at 30 minutes after incision, 30 min after liver resection and in the recovery room. Oxygen delivery decreased significantly (P < 0.05) during liver resection. Oxygen consumption remained low throughout the procedure. We did not discover any flow-dependent change in oxygen consumption. Although our patients persisted a hyperdynamic state throughout surgery, their arterial ketone body ratio remained low. Therefore, it may be necessary to maintain a hyperdynamic state during partial liver resection in order to increase hepatic blood flow.

Radiofrequency Ablation versus Surgical Resection in Elderly Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis

“…These studies suggest possible comorbidities in elderly HCC patients. Compared to RFA, surgery has more complications caused by general anesthesia and systemic hemodynamic changes, consequently leading to increased short-term mortality or in-hospital mortality [36,37]. Due to the characteristics of elderly HCC patients, physicians should consider the treatment safety rather than efficacy [9,38].…”