Hemodynamics After Glucose Loading In Hispanics With And Without Family History Of Type 2 Diabetes

Abstract

Supine and standing lnRMSSDavg were 4.4±0.4 and 3.5±0.5 ms in men, and 4.1±0.6 and 3.1±0.5 ms in women, respectively. Supine and standing lnRMSSDcv were 8.1±3.4 and 10.6±5.4% in men, and 9.8±5.2 and 13.0±4.4% in women, respectively. In men, supine lnRMSSDavg (r=-.62) and standing lnRMSSDcv (r=.55) were associated with cf-PWV (6.2±0.84 m/s; P<0.05), but no associations were observed between HRV indices and AIx75 (2.2±12.3%; P>0.05). In women, supine lnRMSSDavg (r=-.52) and lnRMSSDcv (r=.52), and standing lnRMSSDmean (r=-.51) were associated with cf-PWV (5.8±0.5 m/s; P<0.05), and supine lnRMSSDcv was associated with AIx75 (5.7±9.8%; P<0.05). CONCLUSIONS: Multi-day, self-recorded, HRV measures were related to cf-PWV in young healthy men and women, and AIx75 in women. More numerous and stronger associations between HRV and cf-PWV vs. AIx75 portend a greater autonomic influence on proximal aortic vs. systemic arterial stiffness.