Hemolytic activity and fatty acids composition in the ichthyotoxic dinoflagellate Cochlodinium polykrikoides isolated from Bahía de La Paz, Gulf of California

Dorantes-Aranda, Juan José; Parra, Luz María García-de la; Alonso-Rodrı́guez, Rosalba; Morquecho, Lourdes

doi:10.1016/j.marpolbul.2009.06.007

Cited by 41 publications

(35 citation statements)

References 25 publications

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“…Much of the research on HABs use ex vivo hemolytic activity as a measure of toxicity [15][16][17]45,46], and P. parvum is known to induce hemolysis ex vivo [15][16][17]. To assess whether hemolysis occurs in vivo during P. parvum exposure, blood samples were collected from six of the exposed fish immediately after euthanization.…”

Section: Hemolysismentioning

confidence: 99%

Effects of Harmful Algal Blooms on Fish: Insights from Prymnesium parvum

Svendsen

Andersen

Hansen

et al. 2018

Fishes

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Blooms of the planktonic alga Prymnesium parvum pose a global threat, causing fish kills worldwide. Early studies on the exposure of fish to P. parvum indicate that toxic effects are related to gill damage. The more strictly defined concept of adverse outcome pathways has been suggested as a replacement for the mode of action in toxicology studies. In this study, rainbow trout (Onchorhyncus mykiss) were exposed to P. parvum. During exposure, oxygen consumption was determined by respirometry, and ventilation and coughing rate were determined via video surveillance. Per breath oxygen consumption was calculated to assess the ventilation effort to obtain a unit of oxygen. A second experiment monitored fish behavior to assess recovery. The results indicated that oxygen consumption initially increased, but on average fell below the standard oxygen consumption at 70% relative exposure. Being a function of ventilation frequency and oxygen consumption, the per breath oxygen consumption decreased throughout exposure. Behavioral results determined that short-term P. parvum exposure subsequently caused the exposed fish to seek flow refuge immediately and to a greater extent than unexposed fish. The adverse outcome pathway of P. parvum on rainbow trout is that P. parvum acts as a gill irritant resulting in non-recoverable respiratory failure.

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Section: Hemolysismentioning

confidence: 99%

Effects of Harmful Algal Blooms on Fish: Insights from Prymnesium parvum

Svendsen

Andersen

Hansen

et al. 2018

Fishes

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show abstract

“…Unsaturated fatty acids have also been implicated in toxicity towards finfish and mammalian cells [51,52] causing haemolysis [48,53] and ichthyotoxicity [44]. Toxic fatty acids occur in glycolipids [53,54] or in the free form [48,49,53,55].…”

Section: Lipid Oxidationmentioning

confidence: 99%

Lipids in Marine Ecosystems

2013

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Lipids provide the densest form of energy in marine ecosystems. They are also a solvent and absorption carrier for organic contaminants and thus can be drivers of pollutant bioaccumulation. Among the lipids, certain essential fatty acids and sterols are considered to be important determinants of ecosystem health and stability. Fatty acids and sterols are also susceptible to oxidative damage leading to cytotoxicity and a decrease in membrane fluidity. The physical characteristics of biological membranes can be defended from the influence of changing temperature, pressure, or lipid peroxidation by altering the fatty acid and sterol composition of the lipid bilayer. Marine lipids are also a valuable tool to measure inputs, cycling, and loss of materials. Their heterogeneous nature makes them versatile biomarkers that are widely used in marine trophic studies, often with the help of multivariate statistics, to delineate carbon cycling and transfer of materials. Principal components analysis has a strong following as it permits data reduction and an objective interpretation of results, but several more sophisticated multivariate analyses which are more quantitative are emerging too. Integrating stable isotope and lipid data can facilitate the interpretation of both data sets and can provide a quantitative estimate of transfer across trophic levels.

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“…Studies have also demonstrated that this alga causes rapid mortality in reef building coral (Bauman et al, 2010;Richlen et al, 2010), copepods (Jiang et al, 2009(Jiang et al, , 2010a, other phytoplankton (Tang and Gobler, 2010), shellfish larvae (Ho and Zubkoff, 1979;Tang and Gobler, 2010), bivalves (Ho and Zubkoff, 1979;Tang and Gobler, 2010), and cultured fish Dorantes-Aranda et al, 2009;Tang and Gobler, 2009a). Despite the severe and broad nature of the toxicity of Cochlodinium, the precise compounds responsible for this toxicity have yet to be confirmed.…”

Section: Cochlodinium Toxinsmentioning

confidence: 99%