Hepatic transcriptomic and histopathological responses of common carp, Cyprinus carpio, to copper and microplastic exposure

Hoseini, Seyyed Morteza; Khosraviani, Kave; Delavar, Fatemeh Hosseinpour; Arghideh, Mohammad; Zavvar, Fatemeh; Hoseinifar, Seyed Hossein; Doan, Hien Van; Zabihi, Erfan; Reverter, Miriam

doi:10.1016/j.marpolbul.2022.113401

Cited by 31 publications

(11 citation statements)

References 71 publications

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“…Plants are rich sources of antioxidant compounds; as a result, one of the main benefits of dietary herbal additives is the improvement of the antioxidant system and a reduction of oxidative stress (Mohiseni, 2017;Abdel-Latif et al, 2020a;Abdel-Latif et al, 2020b). The liver has high metabolic rate and is the main organ of detoxification; hence, it possesses high antioxidant capacities (Hoseini et al, 2022b). Modern aquaculture is accompanied by various stressors such as high stocking density and inferior water quality that induce oxidative conditions in fish; so that dietary herbal additives may benefit the host by suppressing such drawbacks.…”

Section: Introductionmentioning

confidence: 99%

Effects of dietary methanolic extract of hyssop, Hyssopus officinalis, on growth performance, hepatic antioxidant, humoral and intestinal immunity, and intestinal bacteria of rainbow trout, Oncorhynchus mykiss

et al. 2022

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The aims of the present study were to assess the effects of Hyssop, Hyssopus officinalis, methanolic extract (HE) on growth performance, hepatic oxidative status, humoral and intestinal immunity, and intestinal bacteria of rainbow trout, Oncorhynchus mykiss. Fish were allocated into twelve tanks for four treatments, receiving diets containing 0, 100, 250, and 500 mg/kg HE for eight weeks. The results showed that dietary HE supplementation induced no significant differences in the growth performance, feed efficiency, and hematological parameters (P > 0.05). HE supplementation significantly increased total leukocyte count and the highest count was observed in 250 mg/kg HE treatment (P < 0.001). Fish in 250 and 500 mg/kg HE treatments exhibited significantly lower lymphocyte (P = 0.001) and higher neutrophil (P = 0.002) percentages; the former exhibited a significantly higher monocyte percentage (P = 0.021). Hepatic superoxide dismutase (100 and 250 mg/kg HE; P < 0.001), glutathione peroxidase (100 and 250 mg/kg HE; P = 0.001), glutathione reducatse (all HE treatments; P < 0.001), and reduced glutathione (250 mg/kg HE; P = 0.046) significantly increased, whereas hepatic malondialdehyde levels (250 and 500 mg/kg HE; P = 0.007) significantly decreased in HE-treated fish. Plasma total protein, albumin, globulin, lysozyme, and alternative complement significantly increased in 250 and 500 mg/kg HE treatments and plasma total Ig significantly increased in 250 mg/kg HE treatment. Quantitative real time PCR found no Streptococcus iniae, Lactococcus garvieae, Aeromonas hydrophila, Yersinia ruckeri, and Vibrio anguillarum in the fish intestines in any treatments. Lactobacillus sp. was detected in the fish intestinal samples, but there were no significant differences among the treatments (P = 0.352). Intestinal defensin (P = 0.044) and interleukin-1 beta (P = 0.0.035) expressions were significantly up-regulated in 100 mg/kg HE; intestinal interleukin-10 (P < 0.001) and tumor necrosis factor-alpha (P < 0.001) expressions were significantly up-regulated in 100 and 500 mg/kg HE; whereas, intestinal interleukin-6 expression was significantly (P = 0.009) up-regulated in 250 mg/kg HE treatments. It is concluded that HE is able to stimulate humoral and intestinal immune responses and hepatic antioxidant capacity. HE effective concentration in rainbow trout may be in the range of 100-250 mg/kg.

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Section: Introductionmentioning

confidence: 99%

Effects of dietary methanolic extract of hyssop, Hyssopus officinalis, on growth performance, hepatic antioxidant, humoral and intestinal immunity, and intestinal bacteria of rainbow trout, Oncorhynchus mykiss

et al. 2022

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“…A few of these articles studied the effect of micro-or nanoplastics on the endocrine growth axis. Some works investigated the effect of microplastics and their combinations with other pollutants at the transcriptomic level, but no reports of genes involved in growth were found (323)(324)(325). Zheng and colleagues (326) investigated the effects of embryolarvae exposure to 500 mg/L of polystyrene microplastic (MP) (5 µm) alone and in combination with ZnO nanoparticles (NPs) on exposed F0 and unexposed F1 larvae of zebrafish.…”

Section: Micro-and Nano Plasticsmentioning

confidence: 99%

The effect of environmental stressors on growth in fish and its endocrine control

Canosa

Bertucci

2023

Front. Endocrinol.

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Fish body growth is a trait of major importance for individual survival and reproduction. It has implications in population, ecology, and evolution. Somatic growth is controlled by the GH/IGF endocrine axis and is influenced by nutrition, feeding, and reproductive-regulating hormones as well as abiotic factors such as temperature, oxygen levels, and salinity. Global climate change and anthropogenic pollutants will modify environmental conditions affecting directly or indirectly fish growth performance. In the present review, we offer an overview of somatic growth and its interplay with the feeding regulatory axis and summarize the effects of global warming and the main anthropogenic pollutants on these endocrine axes.

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“…The concentration of NPs for this study was determined based on previous studies and the results of our preexperiments. 20,33,34 A treatment solution of 100 nm fluorescent NPs with a concentration of 1000 μg L −1 was prepared and 2 mL was added to each well of a 12-well cell culture plate. Healthy embryos at 2 hpf were placed in the 12well cell culture plate to which the treatment solution was added.…”

Section: The Observation Of Fluorescent Nanoplastics In Zebrafish Emb...mentioning

confidence: 99%

“…Many studies have reported that co-exposure to NPs and Cu can promote the accumulation of Cu in common carp and zebrafish. 12,[20][21][22][23] Some previous studies have reported the partial combined effects of MPs/NPs and Cu on fish, such as growth inhibition, oxidative stress, behavioral changes and acetylcholinesterase inhibition. 12,[21][22][23] In particular, the studies of Santos et al focused on the toxic effects of MPs (2 μm, 2 mg L −1 ) and Cu on zebrafish in the early life stages.…”

Section: Introductionmentioning

confidence: 99%

Mitochondrial dysfunction and lipometabolic disturbance induced by the co-effect of polystyrene nanoplastics and copper impede early life stage development of zebrafish (Danio rerio)

ZHANG

et al. 2023

Environ. Sci.: Nano

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Hepatic transcriptomic and histopathological responses of common carp, Cyprinus carpio, to copper and microplastic exposure

Cited by 31 publications

References 71 publications

Effects of dietary methanolic extract of hyssop, Hyssopus officinalis, on growth performance, hepatic antioxidant, humoral and intestinal immunity, and intestinal bacteria of rainbow trout, Oncorhynchus mykiss

Effects of dietary methanolic extract of hyssop, Hyssopus officinalis, on growth performance, hepatic antioxidant, humoral and intestinal immunity, and intestinal bacteria of rainbow trout, Oncorhynchus mykiss

The effect of environmental stressors on growth in fish and its endocrine control

Mitochondrial dysfunction and lipometabolic disturbance induced by the co-effect of polystyrene nanoplastics and copper impede early life stage development of zebrafish (Danio rerio)

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