Hepatitis B among University Population: Prevalence, Associated Risk Factors, Knowledge Assessment, and Treatment Management

Kazmi, Syed Ayaz; Rauf, Abdul; Alshahrani, Mohammed; Awadh, Ahmed Abdullah Al; Iqbal, Zahoor; Soltane, Raya; Eldin, Sayed M.; Ahmad, Altaf; Ansari, Zulqarnain; Zia-ur-Rehman, Zia-ur-Rehman

doi:10.3390/v14091936

Cited by 4 publications

(1 citation statement)

References 29 publications

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“…In addition to predominantly spreading through blood and serum, HBV can also transmit vertically from mother to child. The three most typical ways that HBV is contracted are through unsafe injection practices, sexual contact and vertical transmission (4). HBV infection is one of the most important infectious diseases in dental practice (5).…”

Section: Introductionmentioning

confidence: 99%

Preoperative Hepatitis B seroprevalence and AntiHbs Levels in Children Consulted for Dental Procedures Under Anaesthesia

Sert,

Kaya

2024

Genel Tıp Dergisi

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Background/Aims: Hepatitis B virus infection continues to be a major global and national public health concern. The aim of this study was to examine the seroprevalence of hepatitis B virus in children who were consulted to child health and diseases before dental intervention and to share our findings with the healthcare personnel involved on this subject. Methods: A total of 932 children were enrolled in the study, of which 533 (57.2%) were boys and 399 (42.8%) were girls. In the blood samples taken; hepatitis B virus tests were studied with the Enzyme Linked Immuno Sorbent Assay method. The results of blood samples and demographic data of the patients were evaluated. Results: HBsAg positivity was not found in any of the patients (0%). AntiHbs seropositivity was found in 73.8% of the whole patient population. No statistically significant difference was detected when comparing the anti-HBs levels based on gender. The average age of children with antiHbs seropositive was found to be statistically significant lower than that of those with antiHBs negative. The median anti-HBS antibody levels were significantly higher in the group of children under 5 years old than in the other two age groups older than five years old in our study. When investigating the association between the level of antiHBs and age, a weak negative correlation was found. Conclusions: Our study showed that the antiHbs seropositivity is higher in Konya compared to previous studies. It suggests that the national vaccination program has a positive impact on antiHbs seroprevalence. Our study revealed that children under the age of five displayed the highest levels of anti-HBs seropositivity, while the anti-HBs levels diminished with advancing age.

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Section: Introductionmentioning

confidence: 99%

Preoperative Hepatitis B seroprevalence and AntiHbs Levels in Children Consulted for Dental Procedures Under Anaesthesia

Sert,

Kaya

2024

Genel Tıp Dergisi

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Cross cutting symptoms, liver function and perceived immune status as predictors of quality of life in patients with Hepatitis B and C: the mediating role of social support and resilience

Kazmi,

Iftikhar

2024

Curr Psychol

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A 28-year-old male patient with asymptomatic and multi-drug-resistant HBV infection: a case report

Kazmi,

Rauf,

Latif

et al. 2024

Egypt Liver Journal

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Chronic hepatitis B virus (HBV) infection poses a significant global health challenge, impacting millions of individuals and elevating the risk of morbidity and mortality. Antiviral therapies are the primary treatment for chronic HBV infection, but treatment resistance can occur, leading to poor clinical outcomes and an increased risk of liver complications. This case report presents the clinical trajectory of a 28-year-old male diagnosed with asymptomatic HBV infection in 2016 under the auspices of the Hepatitis Control Program, Government of Azad Jammu and Kashmir, Pakistan. Over 6 years, persistent HBsAg, HBV, and HBeAg were observed, with absent acute markers and co-infections. Initial HBV DNA viral load was 1 × 104 copies/mL in 2016, escalating despite entecavir and pegylated interferons therapy, indicating multi-drug resistance. Tenofovir therapy initially reduced viral load but later exacerbated it, reaching 1.86 × 106 copies/mL in 2022. Liver function abnormalities and lipid profile irregularities persisted. Urine examination consistently showed abnormalities. Pending HBV DNA sequencing results may offer insights into treatment resistance. This case underscores the need for an adaptive approach in managing chronic HBV infections within public health programs. Continuous monitoring, integration of virological and biochemical data, and a tailored treatment strategy are essential for optimizing outcomes in similar cases, stressing the importance of refining therapeutic approaches against chronic HBV infection.

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Hepatitis B among University Population: Prevalence, Associated Risk Factors, Knowledge Assessment, and Treatment Management

Cited by 4 publications

References 29 publications

Preoperative Hepatitis B seroprevalence and AntiHbs Levels in Children Consulted for Dental Procedures Under Anaesthesia

Preoperative Hepatitis B seroprevalence and AntiHbs Levels in Children Consulted for Dental Procedures Under Anaesthesia

Cross cutting symptoms, liver function and perceived immune status as predictors of quality of life in patients with Hepatitis B and C: the mediating role of social support and resilience

A 28-year-old male patient with asymptomatic and multi-drug-resistant HBV infection: a case report

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