Hepatitis B reactivation in chronic hepatitis C patients treated with interferon or pan‐oral direct‐acting antivirals

Risk of hepatitis B virus reactivation with direct‐acting antivirals against hepatitis C virus: A cohort study from Egypt and meta‐analysis of published data

“…However, the review was limited because most of the included studies used patients on IFN‐based regimens, and there were only 2 studies with patients on IFN‐free DAAs. Moreover, the meta‐analysis endpoint was HBV reactivation as defined by the authors of each article, which varied considerably . In the systematic review and meta‐analysis that we present here, we were able to include 18 studies with patients on IFN‐free DAAs and use a common endpoint definition, proposed by the APASL and AASLD.…”